Cell To Systems's Podcast

AI is transforming longevity medicine, but can it replace your doctor?

In this episode of ‪@CellToSystems‬ we dive deep into the promise and peril of AI in longevity medicine. From AI-powered peptide discovery to digital humans managing your front desk, the future is here, but it is not without risk.

In this episode, we uncover:
▪️ AI-powered drug discovery: How machine learning is sequencing peptides a million times faster than humans, and why that's both exciting and terrifying.
▪️ The legal paradox: Why doctors will soon be sued for listening to AI and for ignoring it at the same time.
▪️ The memory trap: How AI scribes are freeing up providers' time but eroding their ability to retain clinical details.
▪️ G.R.A.C.E.: The digital front desk: Quantum's AI that schedules, triages, and communicates 24/7 without ever putting a patient on hold.
▪️ The data dilemma: What happens when AI knows more about your health than you do, and who really owns that information?
▪️ Clinical intuition vs. automation: Why the future of medicine isn't less human - it's more precise.

If you're a provider navigating AI integration, a patient wondering if your data is safe, or a longevity enthusiast tracking the bleeding edge of healthcare tech, this episode will change how you think about the tools you are already using.

Support the show

Most people view sleep as passive downtime. In this episode of ‪@CellToSystems‬, we reframe it as an active, mandatory biological workflow. We dive deep into why sleep is the ultimate system for cellular repair, metabolic health, and cognitive longevity.

1 in 3 American adults doesn't get enough sleep; and up to 70 million Americans chronically suffer from a sleep or wakefulness disorder (NIH; National Academies of Medicine). We explore the terrifying reality of sleep apnea, the controversy of "histamine storms" from leftovers, and why failing to hit deep sleep means your brain is "marinating in its own waste."

Inside this episode:
• The glymphatic shift: How your brain flushes amyloid plaques during deep sleep.
• Metabolic wakefulness: Why glucose drops at 2 AM trigger the "cortisol loop" and how to stop it.
• Clinical triage: Identifying the #1 cause of nighttime cardiac death.
• The wearable trap: Moving from "scorecard anxiety" to using data as a biological dashboard.

Support the show

Are you optimizing your nutrition or just creating a cage around it? If you're tracking macros, using wearables, and still feeling disconnected from your body, this episode of ‪@CellToSystems‬ is your reset. 🍏⌚️🏋️‍♂️

In this episode, high-performance Registered Dietitian Robin Steagall   / bodyscience.rd    joins our panel to unpack the psychology behind performance nutrition and break down the most dangerous mistake in the longevity space: under-fueling. Robin Steagall is the owner and founder of Body Science RD https://bodysciencerd.com/ Her areas of expertise include nutrition planning, metabolism optimization, and long-term weight management.

Most people think they are "optimizing" by eating less and training harder. In reality, they are just triggering their body's panic button. We are breaking down why your metabolism stalls when you "eat clean," why Leonard threw away his health trackers to finally feel better, and why your body sees a calorie deficit as a survival threat rather than a weight loss goal. 

In this episode, you will learn:
• The "skinny fat" cycle: Why calorie restriction that "worked" for weight loss sabotages muscle retention and metabolic health long-term.
• Protein timing myths: Why hitting your total protein intake matters more than obsessing over the post-workout window.
• GLP-1 reality check: How these medications change appetite, hydration, and nutrient absorption, and what that means for performance.
• Food as psychology: Getting real about binge eating, shame, and why willpower isn't the problem. 
• Training your kids (without the shame): How to teach food choices without creating anxiety or disordered eating in the next generation.

Support the show

Is your exercise routine actually aging you?

The science is sobering: muscle mass decreases 3-8% per decade after age 30, and strength declines even faster: 1.5% per year between ages 50–60, accelerating to 3% annually after that (PMC/NIH). Most people will lose around 30% of their muscle mass over their lifetimes, and less muscle means greater weakness, less mobility, and higher risk of falls and fractures (Harvard Health).

In this episode of ‪@CellToSystems‬ , we break down why exercise is more than just aesthetics or weight loss and reveal why the traditional 7-day gym cycle is a myth that may be overtaxing your central nervous system. We move past "gym culture" and into the "prescription for movement," revealing why muscle mass is the primary predictor of lifespan and how to optimize your physical system for longevity.

Here's what makes this urgent: An estimated 5-13% of adults aged 60-70 are affected by sarcopenia, rising to 11-50% for those 80 and above (Harvard Health/PMC). And reduced muscle mass doesn't just affect mobility; it directly decreases metabolic rate, compromises blood sugar regulation, negatively affects cardiovascular health, and is even linked to cognitive decline (JACC).

In this episode, you will learn:
• The 10-Day Training Cycle: Why it is better to abandon the 7-day week for better recovery 
• Exercise in a Pill: How compounds like Creatine and 5-Amino-1MQ can activate the SIRT-1 longevity gene.
• Muscle as Wealth: Why muscle is your "largest glucose sink" and the #1 predictor of how long you’ll live.
• The GLP-1 Muscle Crisis: The hidden danger of modern weight-loss drugs and the "Muscle Tax" you can't afford to pay.
• Exercise Snacks: How 1-minute bursts of movement can outperform 40 minutes on a treadmill.

Support the show

Are your hormones actually optimized, or just "normal"? There's a big difference.

In this episode, we are joined by Dr. Kris Wusterhausen   / drkriswusterhausen  board-certified family physician and age management medicine specialist, for a deep, nuanced conversation on hormone optimization for both men and women.

If you or your provider still believe HRT comes with extreme risks, this episode is a necessary intervention. We cover everything from the biggest misconceptions still circulating in mainstream medicine to why testosterone is not just a "male hormone" to how hormones affect relationships, libido, and long-term health outcomes.

In this episode, you will learn:
• 🔥Why low testosterone is actually a risk factor for prostate cancer (and why replacement therapy doesn’t "feed" it).
• 🧠 The hormonal decline that drives aging (not the reverse)
• 🤫 Why "Normal" lab ranges are failing you, and the critical "forgotten" hormone (Thyroid) that primary care religiously overlooks.
• 💪Growth hormone peptides and their role in body composition and recovery
• ❤️ Why hormone therapy is sometimes the best marriage counseling

Stop accepting fatigue, brain fog, and "the slow fade" as inevitabilities of getting older. It’s time to move from "Cell to System."

🔗 More about Dr. Kris Wusterhausen:
•   / drkriswusterhausen 
• The Resurge Clinic   / theresurgeclinic  https://www.theresurgeclinic.com/ 

Support the show

Think your "normal" cholesterol means you’re safe? Think again.

In this episode of Cell to System, we sit down with world-renowned integrative medicine and cardiology physician Dr. Abid Husain, MD, FACC, ABAARM dr_abidhusain from Boulder Longevity Institute, to dismantle the 40-year-old myths surrounding cholesterol. If you are one of the 30 million Americans taking a statin, or if you’ve been told your LDL is "fine," this conversation is a life-changer.
In this episode, we uncover:
• Why particle size matters more than your total cholesterol number.
• How AI-based CT scans are finding "hot" inflamed plaque that standard tests miss.
• The hidden link between cholesterol-lowering drugs and cognitive impairment.
• How spike proteins and chronic inflammation are changing the landscape of vascular health post COVID.
• Why most primary care doctors are still using outdated "hammer and nail" diagnostic tools.
Stop treating a number and start treating the terrain.

🔗 More about Dr. Abid Husain:
•   / dr_abidhusain 
• Boulder Longevity Institute https://boulderlongevity.com/ 

🎙️ Follow the Cell to Systems Team:
• Leonard Pastrana, PharmD: Co-founder of nuBioAge & nuHx.Health / www.instagram.com/leonardpastrana
• Franck Kacou, PharmD: owner of Progress Pharmacy; co-founder of nuBioAge, nuHx.Health, Source Pharmacy and nuCliniq / www.instagram.com/nubioagewellnessnetwork / www.instagram.com/progresspharmacy
• Suzanne Ferree, MD, FAARM, FSSRP: CEO and Senior Physician of Vine Medical Associates / www.instagram.com/drsferree
• Kristi Fury, CFNP: A board-certified Family Nurse Practitioner; founder of Beyond Health. / www.instagram.com/beyondhealthabq
• Craig Mullen, MSN, FNP, ACNP: Founder of Remedy Functional Health Solutions. / www.instagram.com/remedy.functional.health
• Jock Putney - CEO and founder of Nuvolum, Quantum PRM, Stemodontics / www.instagram.com/jockputney

Support the show

• Are you drinking a gallon of water a day and still dealing with brain fog, fatigue, and slow recovery? You might be hydrating your blood while leaving your cells bone-dry.
In this episode of Cell to System, we are breaking the "Three Buckets" of hydration to reveal why most electrolytes never actually reach the "Engine Room" of your body: the cell. We move past the basic advice of "drink more water" and dive into the world of Intracellular Irrigation.

In this episode, we uncover:
• The Three Buckets of Biology: Why your blood can be hydrated while your cells are literally "deflating."
• The VIP Bouncer: How to use Osmolytes (Creatine, Taurine, and Glutamine) to force water into your mitochondria.
• The Medication Trap: Why GLP-1s, ADHD meds, and Steroids are quietly drying out your system.
• The High-Altitude Protocol: How elevation impacts your cell volume and what to do before your next ski trip.
• Osmolytes vs. Electrolytes: The missing link in your supplement cabinet for muscle protein synthesis and cognitive focus.

If you are on a longevity protocol, using peptides, or simply trying to optimize your energy, this episode provides the foundational blueprint that makes every other treatment work better.

🔗 Mentioned in this episode:
 ▸ NuBioAge iCell WaterTM
https://shop.nubioage.com/products/ic...

🎙️ Follow the Cell to Systems Team:
• Leonard Pastrana, PharmD: Co-founder of nuBioAge & nuHx.Health / www.instagram.com/leonardpastrana
• Franck Kacou, PharmD: owner of Progress Pharmacy; co-founder of nuBioAge, nuHx.Health, Source Pharmacy and nuCliniq / www.instagram.com/nubioagewellnessnetwork / www.instagram.com/progresspharmacy
• Suzanne Ferree, MD, FAARM, FSSRP: CEO and Senior Physician of Vine Medical Associates / www.instagram.com/drsferree
• Kristi Fury, CFNP: A board-certified Family Nurse Practitioner; founder of Beyond Health. / www.instagram.com/beyondhealthabq
• Craig Mullen, MSN, FNP, ACNP: Founder of Remedy Functional Health Solutions. / www.instagram.com/remedy.functional.health
• Jock Putney - CEO and founder of Nuvolum, Quantum PRM, Stemodontics / www.instagram.com/jockputney

🔗 Learn More:
Vine Medical Associates: https://vinemedical.com/
nuBioAge: https://nubioage.com/ 
Remedy Functional Health: https://remedyfunctionalhealth.net/
Beyond Health:

Support the show

Is your muscle "marbled" like a ribeye steak? 🥩

In this episode of Cell to Systems, we pull back the curtain on the metrics that actually determine your "Biologic Future." We move past the bathroom scale to expose Myostasis, a condition where fat quietly replaces your muscle fibers from the inside out, and why "big muscles" can sometimes be a sign of systemic inflammation.

In this episode, we reveal:
• The "Invisible Rot": Why your muscle quality matters more than your muscle size.
• The Phase Angle Secret: The #1 cellular marker you need to track (and why you want it above a 7.0).
• The 900lb Squatter: How an elite athlete got stronger by losing 30lbs of "fatty" muscle.
• The 30-Second Mortality Test: Why the "Sit-to-Stand" and Grip Strength tests predict your lifespan better than any blood draw.
• Peptide Black Market Exposed: The truth about $50 vials, endotoxin contamination, and"sneaky" research companies infiltrating medical clinics.
• The "Picked, Pulled, or Killed" Rule: Kristi Fury’s simple filter for a longevity-first diet.

🎙️ Follow the Cell to Systems Team:
• Leonard Pastrana, PharmD: Co-founder of nuBioAge & nuHx.Health /   / leonardpastrana 
• Franck Kacou, PharmD: owner of Progress Pharmacy; co-founder of nuBioAge, nuHx.Health, Source Pharmacy and nuCliniq /   / nubioagewellnessnetwork  /   / progresspharmacy 
• Suzanne Ferree, MD, FAARM, FSSRP: CEO and Senior Physician of Vine Medical Associates /   / drsferree 
• Kristi Fury, CFNP: A board-certified Family Nurse Practitioner; founder of Beyond Health. /   / beyondhealthabq 
• Craig Mullen, MSN, FNP, ACNP: Founder of Remedy Functional Health Solutions. /   / remedy.f

Support the show

• The world of peptide therapy is moving faster than the regulations can keep up with. In this episode of Cell to Systems, we skip the "Peptides 101" lecture and dive straight into the high-stakes reality of modern cellular medicine.

From the recent regulatory announcements to the "Trust Me, Bro" culture of internet research chemicals, our panel of experts breaks down how to separate legitimate medicine from dangerous experiments. Whether you are a high-performer looking for peak optimization or a healthcare provider trying to build a safe, scalable program, this is your blueprint.

🎙️ In This Episode, We Dive Deep Into:
• The newest peptide news: Breaking down the potential shift of peptides from Category 2 to Category 1 and what it means for the future of compounding pharmacies and patient access.
• The genomic reality: Is personalized peptide therapy a myth or a reality? We discuss how genomic testing is finally allowing for precision longevity medicine.
• The cortisol sabotage: Why your "lifestyle hack" might be failing - how a dysregulated nervous system and high cortisol can render even the best peptide protocols ineffective.
• The hierarchy of evidence: the "Peptide Ladder": from FDA-approved heavyweights to the "Wild West".
• Sourcing truth vs. Sourcing risk: How to spot "Research Use Only" red flags and the extreme dangers of grey-market supply chains.
• The Clinical Operating System: How to move away from "Menu Medicine" and build a governance structure that ensures patient safety, tracking, and reproducible results.

🎙️ Follow the Cell to Systems Team:
• Leonard Pastrana, PharmD: Co-founder of nuBioAge & nuHx.Health |   / leonardpastrana 
• Franck Kacou, PharmD: Owner of Progress Pharmacy; Co-founder of nuBioAge, nuHx.Health, Source Pharmacy and nuCliniq |   / progresspharmacy    / nubioagewellnessnetwork 
• Suzanne Ferree, MD, FAARM, FSSRP: Double board-certified in Family Medicine and Anti-Aging and Regenerative Medicine |   / drsferree 
• Kristi Fury, CFNP: A board-certified Family Nurse Practitioner; Founder of Beyond Health; | 

Support the show

Most people use health data like a scorecard - they see a "failing" sleep grade, and it ruins their day. Experts use data like a dashboard to drive action.

In this episode of Cell to Systems, our panel of longevity experts cut through the "Lab Overload" noise. We reveal why your Apple Watch might be a "behavioral mirror" rather than a clinical tool, and which 5 lab markers actually move the needle for your lifespan.

🎙️ In this episode, you’ll learn:
• The "Oura Ring Paradox": Why tracking your sleep might be causing your insomnia.
• Signal vs. Noise: How to identify the labs that actually predict disease risk.
• The NUHX Approach: Using VO2 Max, Dexa scans, and metabolic testing to build a real roadmap.
• Why a high LP(a) might not be a death sentence if your visceral fat is low.

MEASURE WHAT MATTERS. Stop being a passenger to your data and start being the driver.

🎙️ Follow the Cell to Systems Team:
• Leonard Pastrana, PharmD: Co-founder of nuBioAge & nuHx.Health / www.instagram.com/leonardpastrana
• Franck Kacou, PharmD: Owner of Progress Pharmacy; co-founder of nuBioAge, nuHx.Health, Source Pharmacy and nuCliniq / www.instagram.com/nubioagewellnessnetwork / www.instagram.com/progresspharmacy
• Suzanne Ferree, MD, FAARM, FSSRP: CEO and Senior Physician of Vine Medical Associates / www.instagram.com/drsferree
• Kristi Fury, CFNP: A board-certified Family Nurse Practitioner; founder of Beyond Health. / www.instagram.com/beyondhealthabq
• Craig Mullen, MSN, FNP, ACNP: Founder of Remedy Functional Health Solutions. / www.instagram.com/remedy.functional.health
• Jock Putney - CEO and founder of Nuvolum, Quantum PRM, Stemodontics / www.instagram.com/jockputney

🔗 Learn More:
nuHx: https://nuhx.health/
Remedy Functional Health: https://remedyfunctionalhealth.net/
Beyond Health: https://www.beyond-health.com/
Vine Medical Associates: https://vinemedical.com/
nuBioAge: https://nubioage.com/
Progress Pharmacy:

Support the show