Deja vu: Christian McCaffrey is dealing with a calf issue just days before the San Francisco 49ers’ season opener against the Seattle Seahawks. Should the Faithful be worried? Steph and KP break down McCaffrey’s status, what it could mean for the offense, and the key matchups that will define Week 1.The NFL season is officially here — drop your predictions in the comments and let’s talk Niners football!0:00 Intro2:00 Christian McCaffrey injury update8:35 Game status reports9:35 Game weather report10:15 Changes in Seattle13:16 Seahawks defense16:57 Mike MacDonald vs Kyle Shanahan22:04 Seahawks offense23:08 Seattle wants to run the ball more26:43 What will Alfred Collins' role be?29:29 Ji'Ayir Brown or Marques Sigle?34:10 Run D & tackling faces big test36:45 Bosa & Huff could have advantage, Saleh's plans40:40 Lenoir vs Seattle 🍿45:45 Score prediction & closing remarks