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Heart disease has long been framed as a “man’s disease” – but women are being missed, misdiagnosed, and overlooked in ways that can be life-threatening, especially within South Asian communities where cardiovascular risk often develops earlier and more aggressively.
In this episode, Dr. Komal Patil-Sisodia sits down with advanced imaging and preventative cardiologist, Dr. Ambreen Mohamed, to unpack the evolving science of women’s cardiovascular health, the hormonal shifts that impact risk throughout midlife, and why prevention needs to start far earlier than most people realize.
Together, they explore the subtle symptoms women experience that are too often dismissed, the intersection of menopause, PCOS, pregnancy complications, insulin resistance, and heart disease, and why traditional risk calculators frequently fail to capture the realities of South Asian patients. Most importantly, this conversation reframes prevention not as fear-based medicine, but as empowerment: understanding your risk factors early enough to change the trajectory of your health before disease develops.
Connect with Dr. Mohamed:
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Website
Connect with me:
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Eastside Menopause & Metabolism
Audio Stamps :
00:00 – Dr. Komal introduces Dr. Ambreen Mohamed and sets up the conversation around women’s cardiovascular health, prevention, and South Asian risk
00:00 Podcast Mission Setup
01:05 Meet Dr Ambreen Mohamed
04:38 Why Women Get Missed
07:10 Women’s Heart Attack Symptoms
11:18 Hormones Menopause PCOS Risk
15:06 Pregnancy As Stress Test
18:36 Menopause Hormone Therapy Debate
25:59 South Asian Heart Risk Factors
28:02 Advanced Lipids Lp(a) ApoB
33:07 MASALA Study And Risk Tools
36:27 Perimenopause Lp(a) Spike
37:18 Estrogen and Lp(a) Research
38:11 Who Counts as High Risk
39:55 Doctors Still Learning
42:12 Labs to Ask For
43:31 Insulin Resistance Markers
46:15 Beyond Labs and Blood Pressure
47:52 Sleep Apnea and Heart Risk
48:41 CAC Score When It Helps
50:12 CT Angiogram and AI
54:32 Lifestyle Changes to Start Now
58:48 Advocating at the Doctor
01:02:31 Wrap Up and Where to Find Her
01:04:25 Final Takeaways and Call to Action
Thanks for listening. Find more info about Clearly Hormonal on the website or Instagram.