"Using a weighted blanket increased melatonin concentrations in saliva by about 30 percent”  

#melatonin #blanket #weightedblanket   

Meth, E. M. S., Brandão, L. E. M., van Egmond, L. T., Xue, P., Grip, A., Wu, J., Adan, A., Andersson, F., Pacheco, A. P., Uvnäs-Moberg, K., Cedernaes, J., & Benedict, C. (2022). A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults. Journal of Sleep Research, e13743. https://doi.org/10.1111/jsr.13743

#melatonin #blanket #weightedblanket  

 Meth, E. M. S., Brandão, L. E. M., van Egmond, L. T., Xue, P., Grip, A., Wu, J., Adan, A., Andersson, F., Pacheco, A. P., Uvnäs-Moberg, K., Cedernaes, J., & Benedict, C. (2022). A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults. Journal of Sleep Research, e13743. https://doi.org/10.1111/jsr.13743

"Using a weighted blanket increased melatonin concentrations in saliva by about 30 percent”

  #melatonin #blanket #weightedblanket   

Meth, E. M. S., Brandão, L. E. M., van Egmond, L. T., Xue, P., Grip, A., Wu, J., Adan, A., Andersson, F., Pacheco, A. P., Uvnäs-Moberg, K., Cedernaes, J., & Benedict, C. (2022). A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults. Journal of Sleep Research, e13743. https://doi.org/10.1111/jsr.13743

Daikenchuto may protect the gut against inflammatory bowel disease

Researchers report on the effects of a common herbal remedy on inflammatory bowel disease. A new study shows that DKT -- an herbal medicine containing ginger, pepper, ginseng, and maltose -- reduced the severity of colitis in lab mice by preventing the loss of important gut bacteria and by increasing levels of immune cells in the colon that fight inflammation.

#Daikenchuto #colitis #ibd

Zhengzheng Shi, Tadashi Takeuchi, Yumiko Nakanishi, Tamotsu Kato, Katharina Beck, Ritsu Nagata, Tomoko Kageyama, Ayumi Ito, Hiroshi Ohno, Naoko Satoh-Takayama. A Japanese Herbal Formula, Daikenchuto, Alleviates Experimental Colitis by Reshaping Microbial Profiles and Enhancing Group 3 Innate Lymphoid Cells. Frontiers in Immunology, 2022; 13 DOI: 10.3389/fimmu.2022.903459

Daikenchuto, inflammatory bowel disease, IBD. Colitis, gut, kampo, Lactobacillaceae, Lactobacillus, microbiome, DKT, ginger, pepper, ginseng, propionate, scfa, short-chain fatty acid

Daikenchuto may protect the gut against inflammatory bowel disease

Researchers report on the effects of a common herbal remedy on inflammatory bowel disease. A new study shows that DKT -- an herbal medicine containing ginger, pepper, ginseng, and maltose -- reduced the severity of colitis in lab mice by preventing the loss of important gut bacteria and by increasing levels of immune cells in the colon that fight inflammation.

#Daikenchuto #colitis #ibd

Zhengzheng Shi, Tadashi Takeuchi, Yumiko Nakanishi, Tamotsu Kato, Katharina Beck, Ritsu Nagata, Tomoko Kageyama, Ayumi Ito, Hiroshi Ohno, Naoko Satoh-Takayama. A Japanese Herbal Formula, Daikenchuto, Alleviates Experimental Colitis by Reshaping Microbial Profiles and Enhancing Group 3 Innate Lymphoid Cells. Frontiers in Immunology, 2022; 13 DOI: 10.3389/fimmu.2022.903459

Daikenchuto, inflammatory bowel disease, IBD. Colitis, gut, kampo, Lactobacillaceae, Lactobacillus, microbiome, DKT, ginger, pepper, ginseng, propionate, scfa, short-chain fatty acid

Guar Gum may be a potent Immune regulator

Diets high in guar gum, a common food additive and dietary fibre, limited inflammation and delayed the onset of multiple sclerosis (MS) symptoms in mice, according to new research by members of the University of British Columbia (UBC) Microbiology and Immunology department.

#guargum #ms # neuroinflammation

Fettig NM, Robinson HG, Allanach JR, Davis KM, Simister RL, Wang EJ, Sharon AJ, Ye J, Popple SJ, Seo JH, Gibson DL, Crowe SA, Horwitz MS, Osborne LC. Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis. Cell Rep. 2022 Sep 13;40(11):111328. doi: 10.1016/j.celrep.2022.111328. PMID: 36103823.

Guar gum, fiber, fibre, autoimmune, neuroinflammation, th1, autoimmune encephalomyelitis, dietary fiber, microbiota, experimental autoimmune encephalomyelitis, EAE, multiple sclerosis, MS, CD4+ T cells

Guar Gum may be a potent Immune regulator

Diets high in guar gum, a common food additive and dietary fibre, limited inflammation and delayed the onset of multiple sclerosis (MS) symptoms in mice, according to new research by members of the University of British Columbia (UBC) Microbiology and Immunology department.

#guargum #ms # neuroinflammation

Fettig NM, Robinson HG, Allanach JR, Davis KM, Simister RL, Wang EJ, Sharon AJ, Ye J, Popple SJ, Seo JH, Gibson DL, Crowe SA, Horwitz MS, Osborne LC. Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis. Cell Rep. 2022 Sep 13;40(11):111328. doi: 10.1016/j.celrep.2022.111328. PMID: 36103823.

Guar gum, fiber, fibre, autoimmune, neuroinflammation, th1, autoimmune encephalomyelitis, dietary fiber, microbiota, experimental autoimmune encephalomyelitis, EAE, multiple sclerosis, MS, CD4+ T cells

Folic acid treatment associated with decreased risk of suicide attempts

The study, published in JAMA Psychiatry on September 28th, used data from the health insurance claims of 866,586 patients and looked at the relationship between folic acid treatment and suicide attempts over a two-year period. They found that patients who filled prescriptions for folic acid, also known as vitamin B9, experienced a 44% reduction in suicidal events (suicide attempts and intentional self-harm). Robert Gibbons, PhD, the Blum-Riese Professor of Biostatistics and Medicine at the University of Chicago, the lead author of the study, is hopeful that these findings could improve suicide prevention efforts, especially because of how accessible folic acid is.

“There are no real side effects, it doesn’t cost a lot of money, you can get it without a prescription,” Gibbons said. “This could potentially save tens of thousands of lives.”

#mentalhealth #folicacid #B9

Gibbons RD, Hur K, Lavigne JE, Mann JJ. Association Between Folic Acid Prescription Fills and Suicide Attempts and Intentional Self-harm Among Privately Insured US Adults. JAMA Psychiatry. Published online September 28, 2022. doi:10.1001/jamapsychiatry.2022.2990

Self harm, folic acid, b9, folate, suicide attempts, psychiatry, suicide prevention, safe, suicide prevention efforts, save lives, mental health

Folic acid treatment associated with decreased risk of suicide attempts

The study, published in JAMA Psychiatry on September 28th, used data from the health insurance claims of 866,586 patients and looked at the relationship between folic acid treatment and suicide attempts over a two-year period. They found that patients who filled prescriptions for folic acid, also known as vitamin B9, experienced a 44% reduction in suicidal events (suicide attempts and intentional self-harm). Robert Gibbons, PhD, the Blum-Riese Professor of Biostatistics and Medicine at the University of Chicago, the lead author of the study, is hopeful that these findings could improve suicide prevention efforts, especially because of how accessible folic acid is.

“There are no real side effects, it doesn’t cost a lot of money, you can get it without a prescription,” Gibbons said. “This could potentially save tens of thousands of lives.”

#mentalhealth #folicacid #B9

Gibbons RD, Hur K, Lavigne JE, Mann JJ. Association Between Folic Acid Prescription Fills and Suicide Attempts and Intentional Self-harm Among Privately Insured US Adults. JAMA Psychiatry. Published online September 28, 2022. doi:10.1001/jamapsychiatry.2022.2990

Self harm, folic acid, b9, folate, suicide attempts, psychiatry, suicide prevention, safe, suicide prevention efforts, save lives, mental health

Melatonin's Amazing Research Discoveries:  Episode 1102 FALL 2022

Like vitamin D, melatonin is found throughout the body. Melatonin has been found in many tissues other than the pineal gland and gut mucosa, including the brain, retina, lens, cochlea, trachea, skin, liver, kidney, thyroid, pancreas, thymus, spleen, and reproductive tissues. It is present in nearly all bodily fluids:

#melatonin #antioxidant #chronobiotic

Minich DM, Henning M, Darley C, Fahoum M, Schuler CB, Frame J. Is Melatonin the “Next Vitamin D”?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements. Nutrients. 2022; 14(19):3934. https://doi.org/10.3390/nu14193934

Melatonin, vitamin d, chronobiotic, enterochromaffin, hormone, pineal, gut, darkness deficiency, plant derived, immune-active agent, mitochondrial regulator, migraine, Alzheimer’s disease, multiple sclerosis, fertility, PCOS, lowering body temperature, sleep