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Every year California farmers spray more than 150 million pounds of pesticides to keep insects from ravaging crops like almonds, oranges, and grapes. But when those toxins drift onto nearby farmworkers and communities, they sicken hundreds of people each year. California legislators tried to fix the problem five years ago, but new laws don't appear to have made much of a difference.

It's been twenty years since the Loma Prieta Earthquake ravaged downtown Santa Cruz and damaged San Francisco's Marina District and the Bay Bridge. QUEST looks at the dramatic improvements in earthquake prediction technology since 1989. But what can be done with ten seconds of warning?

Last month, the FBI released a report showing violent crime has dropped for the second year in a row... down nearly two percent in 2008, from a year earlier. Still, many homicide cases go unsolved. A new technology called "bullet microstamping" aims to help change that. But will it work?

This week, conservationists will issue a list of the most endangered national parks, including some in California. There are many ways to measure the health of a park, including the air and the water. This week, Craig Miller looks at an often overlooked vital sign -- the sound.

Why do some people get severely sick from swine flu and others barely feel it? As flu season ramps up, scientists at UCSF's Viral Discovery Center are racing to learn more about the 2009 H1N1 virus, including how it's evolving, and whether our current treatments will remain effective.

We all know that, thanks to our DNA, each of us is a little bit different. Some of those differences are obvious, like eye and hair color, but others are not so obvious, like how our bodies react to medication. Researchers are beginning to look at how to tailor medical treatments to our genetic profiles. Some of the biggest breakthroughs have been in cancer treatment, as Lauren Sommer reports.

Wine grapes are one of the most sprayed crops in California. A growing number of farmers are choosing not to spray and are doing other things for the environment, too. The challenge is there are now so many choices when it comes to green wines, it can be baffling for the eco-conscious consumer. Organic, sustainable, biodynamic, natural... what does it all mean?

A few weeks from now, San Francisco residents will start facing warnings, and even fines, if they fail to recycle, as the city – like many in California – aims to keep ever more garbage out of its landfills. But, after twenty years of curbside recycling and, more recently, composting programs, Californians produce more waste than ever. Amy Standen reports, recycling can only take us so far.

In California, nuclear power has long been a subject that's "radioactive." But recent polls suggest that Californians may finally be warming up to the idea and a new study suggests that a clean energy future may not happen without it. Craig Miller reports on the prospects for a "nuclear revival" in the Golden State.

Months after the federal government enacted stricter standards intended to keep lead out of children's toys, a KQED investigation found merchandise that violates the law still sitting on many Bay Area store shelves. In part two of the series, QUEST looks at the challenges of keeping leaded toys out of stores.