CMEO Webcast
Premiere Date: Thursday, June 8, 2017
This activity offers CE credit for:
Physicians (CME)Nurses (CNE)Pharmacists (ACPE)OtherAll other clinicians will receive a Certificate of Attendance stating this activity was certified for AMA PRA Category 1 Credit™
Credit Expiration Date: Friday, June 8, 2018
Faculty
Maria T. Abreu, MD (Moderator)
Director, Crohn’s & Colitis Center
Martin Kalser Chair in Gastroenterology
Professor of Medicine
Professor of Microbiology and Immunology
University of Miami Miller School of Medicine
Miami, FL
Arthur A. Kornbluth, MD
Clinical Professor of Medicine
Inflammatory Bowel Disease Center
Henry D. Janowitz Division of Gastroenterology
Mount Sinai School of Medicine
New York, NY
Miguel Regueiro, MD, FACP, FACG, AGAF
Professor of Medicine, Professor of Clinical and Translational Science
University of Pittsburgh School of Medicine
Associate Chief, Education
Division of Gastroenterology, Hepatology, and Nutrition
Clinical Medical Director of Inflmmatory Bowel Disease
Senior Medical Lead of Specialty Medical Homes
University of Pittsburgh Medical Center
Pittsburgh, PA
Statement of Need
Ulcerative colitis (UC) is an inflammatory bowel disease with a progressive course characterized by exacerbations and remissions. Traditionally, the goals of therapy for UC have entailed resolution of clinical symptoms such as rectal bleeding, bloody diarrhea, abdominal cramps, pain, and fatigue. However, treatment goals for UC have evolved to a treat-to-target strategy with targets such as mucosal/endoscopic healing, histologic healing, or deep remission (i.e., clinical, biochemical, and endoscopic remission) with the objective of preventing structural damage and disability. Conventional therapies have not been uniformly effective in achieving these aims, necessitating augmentation with steroids and carrying adverse risk often requiring discontinuation.
There has been an exponential growth in the pursuits of better targeted therapy to optimize IBD clinical outcomes. IBD therapies that explore new targets and inflammatory pathways are emerging to address the current treatment gaps observed with conventional and biologic therapies.