The U.S. continues to notch record Covid-19 infections, with the national seven-day average of daily new cases hitting 170,855 on Sunday, according to a CNBC analysis of Johns Hopkins University data. It’s possible the numbers will get a little more opaque heading into the holiday weekend. Kelly Hancock, Cleveland Clinic’s chief caregiving officer, says there are about 970 caregivers currently out of work due to Covid-19. But Covid cases are continuing to rise in the state, doubling in the past three weeks. She joins Shep Smith to talk about the situation. CNBC’s Kayla Tausche reports the General Services Administration has informed President-elect Joe Biden that the Trump administration is ready to begin the formal transition process. Plus, Macy’s Thanksgiving parade…covid style.

Pfizer has applied for emergency approval from the FDA, but how will the vaccine get to Americans? The Covid death rate is rising as health care workers are pushed to the brink. With the CDC urging people to stay in place this Thanksgiving, demand for smaller turkeys has skyrocketed – find out how farmers faring. Plus, the devastating aftermath of Hurricane Iota.

One week out from Thanksgiving, coronavirus cases are still on the rise across the U.S. Health experts are warning against travel and large gatherings for the holiday, encouraging Americans instead to stay home and slow the spread of the virus. New Jersey Governor Phil Murphy discusses new restrictions and why the state isn’t following New York City’s lead in closing down in-person instruction. NBC’s Steve Patterson reports that ski resorts have shut down in New Mexico. If the shutdown continues till Christmas, it will impact 40 percent of their business. People are buying vacation homes in areas like Lake Tahoe; Bend, Oregon; Bridgeport, Connecticut; and the Jersey Shore. CNBC’s Diana Olick discusses the surge in vacation home sales as people continue to work from home. Plus, virtual learning, election results and food insecurity.

Pfizer and BioNTech says that a final data analysis found their coronavirus vaccine was 95% effective in preventing Covid-19 and appeared to fend off severe disease. Dr. Laura Forman, Kent Hospital chief of emergency medicine, says Rhode Island hospitals are running out of space as coronavirus cases continue to rise. She says the U.S. is at risk of running out of essential resources to combat Covid-19. President Donald Trump is still barring President-elect Joe Biden from receiving the classified intelligence and threat briefings typically given to presidents-elect. Still, Senate Majority Leader Mitch McConnell pledged the presidential transition would be orderly. CNBC auto and airline industry reporter, Phil LeBeau, says Boeing’s 737 Max will soon fly again. The Federal Aviation Administration says changes in software, design, and training have made it safe to operate after two fatal crashes. Plus, migrant children, money mules and a relief bill.

The U.S. has surpassed 11 million coronavirus cases, with more than a million new cases reported in just the last week, and hospitals are being pushed to the breaking point. Dr. Michael Osterholm, a member of Joe Biden’s Covid-19 advisory board, discusses best practices to reduce transmission of the virus. President Trump’s administration announced troop withdrawals in Iraq and Afghanistan today, in spite of many military experts recommending against it, including former Defense Secretary Mark Esper. Mad Money host Jim Cramer joins Shep Smith to talk about new traders and why markets are going up despite the pandemic. Plus, former International Space Station commander, Leroy Chiao, discusses the NASA-SpaceX mission to transport astronauts to the ISS.

The U.S. has now recorded more than 11 million Covid-19 cases, tallying 1 million new cases of the virus in under a week. As outbreaks worsen, some state and local officials are re-imposing lockdown measures and major drug makers are releasing promising vaccine trial data. Moderna said today its vaccine candidate is more than 94% effective. President-elect Joe Biden said “more people may die” from the coronavirus if the Trump administration doesn’t begin coordinating with his team on plans to vaccinate more than 300 million Americans against the virus. SpaceX’s Falcon 9 rocket crackled through the sky Sunday evening, carrying the company’s Crew Dragon spacecraft “Resilience” to orbit and marking the beginning of a new era of human spaceflight for NASA. Plus, March Madness, Hurricane Iota and Covid-killings fans.

The U.S. recorded more than 150,000 new Covid cases on Thursday for the first time since the pandemic took hold in the country roughly nine months ago. The seven-day average of daily new infections now stands at 131,445 — 32% higher than this time last week — according to a CNBC analysis of Johns Hopkins data. State and local leaders are again imposing tough restrictions in an effort to tamp down spread ahead of the colder holiday season. Top advisors on President-elect Joe Biden’s transition team spoke of their growing concerns today over the Trump administration’s continued refusal to allow Biden to receive briefings on national security and on the federal coronavirus response. North Korea and Russia are still trying to hack some of the world's most prominent coronavirus vaccine researchers, cybersecurity researchers said today. Plus, a historic move for women in sports and Hollywood is back.

Daily new cases of the coronavirus continue to rise in the U.S., setting fresh records. More than 143,000 new infections were recorded on Wednesday, according to newly revised data from Johns Hopkins University. That’s the highest single-day tally yet. Across the country, families are deciding how, when and where to get together for the holiday season — if at all. Top Republican Sen. Chuck Grassley said President-elect Joe Biden should be receiving classified intelligence briefings from the Trump administration. President Donald Trump has not conceded the race to Biden, and the Democrat’s transition efforts have been stymied by a key agency’s refusal to formally acknowledge him as the winner. At least 13 Republican women are joining the 117th U.S. Congress after dominating the 2020 elections, making history for the highest number of women in the House of Representatives. Plus, Uber and Lyft spent million to pass a law designed to avoid hiring drivers as employees.

Andy Card, former White House chief of staff, discusses the seriousness of President Trump’s refusal to concede the election and how that can impact national security. Card says if the transition of power had happened faster when President Bush won the election, 9/11 may not have happened. The Pentagon elevated three Trump loyalists to powerful positions a day after the sudden termination of Secretary of Defense Mark Esper and following the resignations of multiple senior officials in the Defense Department. Epidemiologists, scientists and public health officials are warning that the United States has yet to see the most difficult days of the coronavirus outbreak. Plus, Georgia’s senate race, video games and special Veterans day story.

The number of coronavirus cases continues to rise globally, yet positive news about a vaccine and drug treatment helped to drive a stock market rally on Monday. Pfizer and BioNTech said their coronavirus vaccine was more than 90% effective in preventing Covid-19 among those not previously infected. President-elect Joe Biden said that the Trump administration’s refusal to authorize the start of the official transition process “does not in any way change the dynamic of what we’re able to do.” Lawyers working to reunite migrant families separated by the Trump administration before and during its "zero tolerance" policy at the border now believe the number of separated children for whom they have not been able to find parents is 666, higher than they told a federal judge last month, according to an email obtained by NBC News. Plus, veteran homebuyers and Beyoncé’s partnership with Peloton.