Coccidioidomycosis, also known as Valley Fever, is a fungal infection. The infection is acquired through inhalation of airborne arthrospores from disturbed soil. Once inhaled, the spores transform into spherules within the host's lungs, leading to a localized or disseminated infection. In this episode, Dr. Brandon Dominguez and Dr. Cathy Campbell sit down with Kalyn Green, assistant section head for serology, to cover clinical signs, diagnostics, and result interpretation.