Many patients experience neurocognitive deficits, PTSD, and generalized weakness and disability following an intensive care unit (ICU) stay. JAMA Medical News Senior Writer Rita Rubin talks with E. Wesley Ely, MD, MPH, a professor of medicine at Vanderbilt University School of Medicine, about ICU aftereffects, post-acute COVID-19 syndrome, and how the coronavirus pandemic, particularly hospitals’ restrictions on visitors, impeded progress made since the 1990s in caring for the critically ill.

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We know that the pandemic caused millions of people to lose their jobs, and potentially their job-based insurance, and yet new survey data showed surprisingly small changes in uninsurance rates at the end of 2020. Kate Bundorf, PhD, from the Sanford School of Public Policy at Duke University and Jessica Banthin, PhD, of the Urban Institute talk to JAMA Health Forum Deputy Editor Melinda Buntin about these trends and the role played by Medicaid and exchange coverage. JAMA Health Forum Editor John Ayanian and Melinda Buntin also discuss other recent work about health insurance coverage and the ACA that has appeared in JAMA Health Forum.

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Interview with Alexander T. Hillel, M.D., author of Quantifying Viral Particle Aerosolization Risk During Tracheostomy Surgery and Tracheostomy Care

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The COVID-19 pandemic has had far-reaching effects on the use of health care services. Dr Nora Becker of the University of Michigan talks about her research on reductions in the use of women’s preventive health services, and JAMA Health Forum Editors Dr John Ayanian and Dr Melinda Buntin discuss other JAMA Health Forum pieces on the effects of state “reopenings” on COVID-19 hospitalizations and deaths, the effects of day care closures on women’s participation in the labor force, and news about nursing home outbreaks of COVID-19.

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Lung transplantation has become an option of last resort for a small subset of patients with COVID-19-related acute respiratory distress syndrome (ARDS) or pulmonary fibrosis. Ankit Bharat, MD, chief of Thoracic Surgery and director of Lung Transplant and ECMO at Northwestern Memorial Hospital in Chicago, discusses his experience performing lung transplants for patients with respiratory failure due to COVID-19, including the first successful double lung transplant in the US for a patient with COVID-19-related ARDS.

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Researchers Tie Severe Immunosuppression to Chronic COVID-19 and Virus Variants; An Inside Look at a Post–COVID-19 Clinic; COVID-19 and the “Lost Year” for Smokers Trying to Quit

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COVID-19 leaves some people with a troubling constellation of symptoms that has been known as long-haul COVID but now has a more formal name: postacute sequelae of SARS-CoV-2 infection (PASC). Currently, 33 states in the US have at least 1 clinic dedicated to caring for patients with PASC. Aluko Hope, MD, a pulmonary and critical care physician, cofounded the Montefiore-Einstein COVID-19 Recovery Clinic in New York in 2020. Now the medical director of the Long Covid-19 Program at the Oregon Health & Sciences University, Dr Hope provides insight into the care provided at a post-COVID-19 clinic.

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Noninvasive ventilation (NIV) may help COVID-19 patients in respiratory failure avoid invasive mechanical ventilation but may also lead to delays in intubation with potential for worse clinical outcomes.

Domenico L. Grieco, MD, of Fondazione Policlinico Agostino Gemelli IRCCS in Rome, Jesse B. Hall, MD, of the University of Chicago, and Laveena Munshi, MD, MSc, of Sinai Health System/University Health Network of the University of Toronto join JAMA's live Q&A series to discuss helmet NIV, high-flow nasal oxygen, and other NIV modalities in the management of hypoxic coronavirus patients. Recorded March 25, 2021.

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The Price of Success—How to Evaluate COVID-19 Vaccines When They’re Available Outside of Clinical Trials; When the Human Voice Speaks Volumes About Lung Function; COVID-19 Vaccines vs Variants—Determining How Much Immunity Is Enough

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Coronavirus trends, variants, vaccines, treatment, and more. JAMA Associate Editor Preeti Malani, MD, MSJ, also from the University of Michigan, and Emory University School of Medicine's Carlos del Rio, MD, return to JAMA's Q&A series to discuss the latest in COVID-19 medicine and public health. Recorded March 15, 2021.

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