You're off to college or  grad school. How do you get started on making a new set of friends? The Ladies offer advice that's applicable to just about anyone starting from scratch.

You're the designated helper…you drive them to their appointments, cook when they're sick, loan them money, and yet when you need a favor, no one's around. The Ladies discuss how and when to help a friend, and when and how to say no, and your own responsibility when people take advantage of your good nature.

Why does there have to be a favorite? Your mom can't stop talking about how much better your sibling is…but what does she say to your sibling when you're not around? The fascinating dynamics that bubble over when someone stirs the pot. Plus, a follow-up from one of our most fascinating letters this year!

What do you do when a friend fails to pick up on your hints? And what do you do when a friend takes credit for things that don't involve her? The Ladies discuss the sometimes strange manifestations of good intentions, and how to learn to choose positivity over frustration.

Your friend is lovely, intelligent and kind…and her life is in the toilet all the freakin' time. You, on the other hand, have your act pretty much together. How do you create balance and avoid being an unpaid therapist? How can you avoid every conversation circling back to her endless problems while still being there for her? The Ladies discuss, plus a horrifying Embarrassing Personal Problem Kristan finally has the courage to describe.

A glimpse into the mind of "that" friend whose rough patch lasts longer than she wants it to…and how she recognized the drain this put on her friendships. The Ladies weigh in on coping mechanisms for both sides when a friend is flailing.

How do you stay friends with a couple after a divorce? What if you want to be friends with the new woman? Plus, hints for heaving dead groundhogs from your backyard, and how to stay cool in this weather!

Is it ever okay to walk away from a friendship without a word? Two letters ask the same question: Can I be done with her yet? But the Ladies are intrigued! Is that what our letter writers really want? Plus, Joss's dog, the infamous and fabulous Glory, scratches her itchy spots whilst the Ladies drink cheap Chardonnay and ponder life's difficult questions.

Sorry for the technical snafu! Once more, with feeling… You're all friends at work…except for that one person who kills everyone's happy vibe and messes with productivity. What do you do? What should you ask your boss? Are you required to like someone just because you work together? How far is "nice" supposed to go? The Ladies discuss, and Kristan talks about self-care, even when it sucks and you feel embarrassed. 

What if you're mostly happy without friends? How do you explain that to people who might make overtures? The Ladies get a unique letter from a listener who sounds happy in her solitude but is afraid she might be missing out.