Oh, the many juicy problems with "Grace," not her real name! She's competitive, judgey, holier-than-thou…and the thing is, you adore her grown daughter, and vice versa! Can you sidestep the mom and just be friends with the now-adult girl you watched grow up? The Ladies think yes…but tread carefully.

In this episode, a caring friend is concerned her friend is getting TOO much therapy from too many sources while she seems to grow less and less happy. Does she speak up? Can she help in any way? Or should she just mind her own business?

You and your friend find yourself living in the same city. Problem is, you don't party like you used to, are trying to clean up your act and be an adult, and you're not sure this friend is going to help the cause. Does this mean you should gently part ways, or can this friendship survive in other ways? The Ladies weigh in, and Joss overshares her recent lip fungus.

TW: This episode deals with unwanted touching and intoxication. The National Sexual Assault Hotline number is 1-800-656-4673. What is the role of a friend when you're drunk and in a bad situation? What kind of reaction should a good friend offer? What expectations should you have in a crisis of this nature? 

She's in your friend group, this bitter, angry, self-centered drama queen, and she's telling you where and when you can show up and what the consequences will be if you disobey. Call the police? Or talk to the other friends? The Ladies recommend the latter with what we think is a pretty awesome solution.

You love your boyfriend, but you can't stand his friends…and especially his friend's baes, who seem to go out of their way to make you feel unwelcome. Really, really unwelcome. What do you say to your honey about the tricks, nastiness and exclusion you're dealing with? Is there a way to be friends with this pack of jackals?

Whoo-whee! The in-fighting, the ignored birthdays, the gossiping and bitchery in this neighborhood make the Ladies  bang our heads against the table. This letter writer and her friends give female friendship a bad name. Deliciously bad behavior all around!

How much consideration should your friends give you when you feel you're ultra-sensitive? How can you avoid feeling hurt and rejected when the issue may actually be a scheduling conflict and nothing more? The Ladies discuss how to avoid FOMO and that feeling of rejection when you're not included or just can't make it to an event.

Note to Selves: If you feel yourself wanting to scream, "Shut up, ____!!!!" during a conversation with a friend, it's generally not a good sign. The Ladies get the giggles over this one, and Kristan shares another wardrobe malfunction in front of an innocent man.

Ah, youth. Sometimes, they just don't know what to say (same is true with adults, of course). The Ladies weigh in on "Van-Nessing" a friend who recently came out and talk about how to negotiate those awkward waters when you're friends with both people and everyone is uncomfortable.