Dr. David Perlmutter — author of Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life — returns to the podcast to reveal shocking research on the role of gut bacteria in depression, ADHD, Alzheimer’s, and autism.

Here's what we talked about:

2:27 – A disaster for medicine? The big problem with looking at the body as different, separate parts and thinking of bacteria as a problem.

6:36 – It all starts in the gut. The set-point of inflammation, the long list of diseases associated with it and why treatments for them don’t always work.

12:35 – What does an optimal microbiome even look like?

14:54 – The power of dirt and how our obsession with “dangerous” germs could be doing us more harm than good.

17:47 – The importance of diversity in the gut and a few things you can do to help your gut help your body.

22:05 – The 3 important brain chemicals your gut makes to keep you healthy. Plus, more evidence for the gut-brain axis and how you can use it as a powerful approach for treating some major disorders.

29:46 – What’s really behind depression and anxiety? The link between gut health and mental health.

34:46 – The biggest problems with feeding out microbiome the standard american diet and what you can do to fix it. (Put down that diet soda.)

39:11 – Some awesome studies about more ways our gut impacts our lives…and can even change your perception of the world around you!

42:31 – Is gut trouble the root cause of ADHD and Autism? How treating the smoke and ignoring the fire is getting us into trouble and some new ideas from science about curing these conditions.

53:17 – Will we ever see widespread support for probiotics and nutritional supplements? Dr. Perlmutter gives us his take.

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Hosted by Sean Croxton of Underground Wellness.