1/ The CDC said Americans who are fully vaccinated can safely go without masks or physical distancing in most cases, including indoors or in large groups. CDC Director Rochelle Walensky called the updated CDC guidance an “exciting and powerful moment,” which offered the country a renewed hope that a return to pre-pandemic “normalcy” is achievable as more people get vaccinated. Biden, calling it “a great day for America,” added that “It’s been made possible by the extraordinary success we’ve had in vaccinating so many Americans so quickly.” More than 154 million Americans have had at least one shot and 117 million are fully vaccinated – 35% of the population. Under the new guidance, which is based on recent real-world studies from Israel and the U.S., fully vaccinated people can resume domestic travel without needing to get tested before or after, and they do not need to self-quarantine. They also do not need to quarantine following exposure as long as they are asymptomatic. (NBC News / CNN / Washington Post / New York Times / CNBC / NPR)

2/ Jobless claims fell to a new pandemic low of 473,000 last week. The 2019 pre-pandemic weekly unemployment average, however, was 218,000. At least 13 Republican-led states, meanwhile, are terminating their involvement in federal pandemic-related unemployment programs early, which include the extra $300-a-week payments. (Wall Street Journal / Axios / The Hill)

3/ A Florida politician – and Rep. Matt Gaetz associate – is expected to plead guilty. Joel Greenberg previously pleaded not guilty to several charges, including stalking, wire fraud, and sex trafficking of a minor, but has been cooperating with the Justice Department since last year, providing investigators with information about encounters he and Gaetz had with women who were given cash or gifts in exchange for sex. The investigation into Greenberg spawned the sex-trafficking investigation into Gaetz. Multiple women paid by Greenberg have said they felt pressured to drink, do drugs, and then have sex with him. (Washington Post / Orlando Sentinel / NBC News / Daily Beast)

4/ The Republican, QAnon-supporting congresswoman from Georgia aggressively co...