Joe and Eric review breaking news out of Washington. Eric gives a deep cut on the spending crisis and what is in store for both the house andpp senate. Plus McCarthy grief.

Over the next three episodes Joe and Eric speak with Mark Paoletta, a distinguished attorney in Washington, a former oversight lawyer on Capitol Hill, and the editor/author of the book Created Equal: Clarence Thomas in his Own Words. This episode explores how the new Republican House majority should conduct oversight. The discussion centered on Mark’s experience investigating the malfeasance at Enron, WorldCom, and Global Crossing, as well as his thoughts on how Congress can inform the public and itself about fraud and abuse in the private sector and within the executive branch. This interview was recorded in early November 2022 just after the new majority was declared in the House of Representatives.

Common misconceptions and why pharmaceutical market is so different. List price, co pays and deductibles, oh my. Bio similars v small molecule, how the evolution here promises great things. Competition is real and generates real savings, and deflation. Opportunity for savings was real, IRA causing disruption to that. Cell and gene therapies are just the latest revolution for patients therapies: branded drugs, generic medicines, small molecule, bio similar. Who pays for these high cost, high reward solutions. How does performance play a role?

Discussed: Batch processing versus Continuous flow technology to onshore manufacturing of medicine. The way we increase the reliability of the supply chain is embrace innovation and bring this close to home. National security is improved as well. Supply driven shortages is again a factor, replacing the Covid crisis “demand “driven shortages. On, or near, shore needs to continue. Also discussed: Manufacturing is facing R&D impacts and the IRA is making substantial impact. Uncertainty and changes to research and development are expected not a theory. 

When the government constrains the price they pay, the price paid by everyone else goes up. 

Who better to hear from about the condition of the condition of shortages dogging the healthcare supply chain than someone closest to the issue. David Senior is a longtime official with AmerisourceBergen, one of the world’s largest players in that chain. He discusses the historical challenges as well as the pressures of deflation on supply.

Naomi wraps the third segment with a flourish of innovative thought. About how much value is being added by the latest developments in medicine, how the shrinking cost of most drugs are spurring market choices, and how states are driving some exciting developments in health public policy. Plus the importance of staying healthy as we age.

The conversation continues with helpful insights- and cautions- about regulating AI, observations about the ability of Washington to keep up with the pace of change, and how we need to reimagine our approach. Also the invidious efforts to ration cures through the IRA under the cover of price controls. Bureaucracies and political agendas are stepping in to decide that they know better than patients and doctors about the value of your life.

Goldwater institute health expert, Naomi Lopez, shares her view on why artificial intelligence should not be feared, and can bring great advantages to medicine. elements of it have also been around for a long time, powering every day items like driver assist and crash avoidance. Naomi also talks about her work on behalf of “right to try” and the help it has delivered to people who have been frustrated by slow FDA approval’s.

Recorded on 7/20- the same day the Stamford University president was forced to resign - Dr. Jay offers comment (50:10) on the hostile work environment allowed on campus.

The sad and painful story of how the government, big tech, and academia conspired to suppress voices. Blacklisting at Twitter, ruined careers, and zero tolerance for questioning use of masks on children, the efficacy of vaccinees, and lockdowns. The federal government's implied and real threats to ensure censorship. and the terrible price price paid that will echo through generations. Dr. Jay shares ideas on how to restore public trust and improve the scientific community.

You can also see this interview on our YouTube page here:https://youtu.be/8HBeapB0nws

The importance of growing the economy, the promise of AI, and why the future will brighter we needn’t be afraid.