Professor Jon Beckwith from Harvard University discusses the profound ethical implications of scientists creating artificial life forms in laboratory settings. As a pioneering geneticist who made breakthrough discoveries in the early days of genetic research, Beckwith now expresses serious reservations about the direction of modern biotechnology. The conversation centers on recent announcements by researchers planning to create single-celled organisms with the minimum genetic material necessary to sustain life, essentially manufacturing living beings from scratch. Beckwith explores the scientific hubris involved in playing God with the fundamental building blocks of existence and the potential catastrophic consequences if these artificial organisms escape containment. He discusses his transformation from an enthusiastic genetic researcher to a cautious advocate for ethical oversight in biological sciences. The discussion examines how creating hybrid organisms using human stem cells to produce human sperm in mice represents a troubling leap toward a brave new world of biological manipulation. Beckwith's Harvard perspective provides crucial insight into the scientific community's responsibility to consider long-term consequences rather than pursuing knowledge without moral boundaries.