Perimenopause can bring physical and emotional changes that leave many women feeling unsettled. Kathryn Macaulay, M.D., Director, UC San Diego Menopause Health Program, explains how hormonal shifts and changing menstrual cycles shape this stage of life. Macaulay examines symptoms such as irregular periods, hot flashes, and mood changes, along with broader concerns including weight, overall health, and contraception. This discussion helps clarify why symptoms vary widely, why care should be individualized, and why women do not need to panic as they move through this transition. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41362]