Aging published this theory article on November 17, 2018, entitled, “Disease or not, aging is easily treatable,” by Dr. Mikhail V. Blagosklonny from the Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY.
Abstract:
Is aging a disease? It does not matter because aging is already treated using a combination of several clinically-available drugs, including rapamycin. Whether aging is a disease depends on arbitrary definitions of both disease and aging. For treatment purposes, aging is a deadly disease (or more generally, pre-disease), despite being a normal continuation of normal organismal growth. It must and, importantly, can be successfully treated, thereby delaying classic age-related diseases such as cancer, cardiovascular and metabolic diseases, and neurodegeneration.
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DOI - https://doi.org/10.18632/aging.101647
Full text - https://www.aging-us.com/article/101647/text
Correspondence to: Mikhail V. Blagosklonny email:
[email protected]Keywords: gerossuppresants, senolytics, longevity, lifespan, aging
About Aging
Launched in 2009, Aging publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.
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