Orthostatic (postural) hypotension is an excessive fall in blood pressure (BP) when an upright position is assumed. The consensus definition is a drop of more for 20 mm Hg systolic, and 10 mm Hg diastolic, or both. Symptoms of faintness, light-headedness, dizziness, confusion, or blurred vision occur within seconds to a few minutes of standing and resolve rapidly on lying down. Some patients experience falls, syncope, or even generalized seizures. Exercise or a heavy meal may exacerbate symptoms. Most other associated symptoms and signs relate to the cause. What is Postural orthostatic tachycardia syndrome (POTS)? In these topic Pathophysiology, Etiology, Evaluation, Treatment, Geriatrics Essentials and Key Points of Orthostatic Hypotension are discussed.