Lindsay Moreland-Head, Pharm.D. (@morelandln) describes the pathophysiology of intravascular versus tissue congestion in Acute Decompensated Heart Failure (ADHF), explains the mechanisms of diuretic resistance in ADHF and why non-inotropic strategies may help augment diuresis and discusses the literature on non-inotropic strategies to decongest patients and overcome loop diuretic resistance in ADHF.

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