It’s taken less than a year for scientists to develop what appears to be an effective vaccine against the coronavirus. Drugmaker Pfizer and its German partner BioNTech delivered dazzling preliminary results in a large patient trial this month, and just today Moderna announced that its vaccine also looks extremely effective. But creating a vaccine is only part of the challenge. Jason Gale spoke with top US infectious-disease doctor Anthony Fauci about another impediment to a successful vaccination strategy: people not wanting to take it.

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