Dr. GPCR Podcast

Undergraduate BSc with Honours in Pharmacology from University of Sydney (1987, snake neurotoxins), Ph.D. from Department of Pharmacology, University of Washington (1992, mentor Charley Chavkin, sigma receptors). Postdoc with Graeme Henderson (Bristol, opioids and Ca signaling) and Mac Christie (Sydney, opioids in neurons, novel spider toxins). Grant-funded independent research positions from 2001 at University of Sydney (opioids and sensory neurons), Vollum Institute Portland (visiting scientist with Ed McCleskey, sensory neuron properties); Pain Management Research Institute (more opioids, cannabinoids and T-type Ca channels) and Brain and Mind Research Institute (Sydney). 2009, appointed Professor of Pharmacology at Macquarie University. Focus on study of drugs and toxins on GPCR (opioid, cannabinoid receptor) and ion channel (K, Ca, TRP channel) function; mostly electrophysiology and fluorescence-based reporters, but can grind and bind. Currently pursuing molecular pharmacology of phytocannabinoids and novel synthetic cannabinoids, with a focus on efficacy and novel targets. Interested in orthosteric and allosteric interactions, and still looking for some bias ... anywhere ... these days human only.

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

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Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

To read the full #Newsletter click here: 

https://www.drgpcr.com/september-2021/

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

Tom Sakmar is a physician-scientist and Rockefeller University professor dedicated to drug discovery and chemical biology research, mainly involving GPCRs. He and his artist/designer wife, Karina Åberg, have three teenage children.

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

Dr. Sudha Shenoy is currently an Associate Professor in Medicine & Cell Biology in the Division of Cardiovascular Medicine, Duke University Medical Center. She received her Ph.D. from Oklahoma State University and completed her postdoctoral training with Dr. Robert J. Lefkowitz (Nobel Laureate, 2012) at Duke University. Dr. Shenoy’s postdoctoral research discovered that ubiquitination of mammalian G protein-coupled receptors is a tag for lysosomal degradation, whereas ubiquitination of the adaptor protein, β-arrestin, is a tag for receptor internalization and formation of signaling endosomes. Her laboratory has continued to work on identifying the molecular mechanisms that ascribe ubiquitin code on GPCRs and β-arrestins. Current efforts aim to understand the regulation of GPCR and beta-arrestin signaling in the heart and vascular endothelium by the deubiquitinating enzymes USP20 and USP33.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

Nyla is a Senior Scientist on the Scientific Support Team at Addgene. She received her Ph.D. at the University of Pittsburgh and continued her postdoctoral research at the University of Vermont studying cellular signaling, biosensors, and optogenetics. Nyla supports biomedical research by connecting researchers with resources and promoting reproducible science.

About Dr. Michael Lemieux

''My name is Michael (Mike) Lemieux and I am a Connecticut native. I completed my Ph.D. in molecular and cell biology at UConn and then joined Addgene as a Quality Control Scientist in 2015. Since then I transitioned into a Scientific Support role to leverage my passion for helping people! Beyond my interest in science, I am a strong advocate for graduate education reform and I love to write.''

Dr. Jason Nasse is a senior scientist at Addgene specializing in the use of AAV viral vectors. He obtained his Ph.D. in Neuroscience from Ohio State University focusing on synaptic plasticity and adrenergic receptor modulation of both pre-and postsynaptic properties. By taking a very non-traditional path to obtain a Ph.D. Dr. Nasse has had the opportunity to experience how science is performed across different sectors and around the country. Prior to his role at Addgene, Jason held roles in academia, big pharma, and non-profit research organizations.

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.yo&a

Simone Prömel is currently a professor of cell biology at the Heinrich Heine University Düsseldorf, Germany. Being a biochemist by training, she completed her Ph.D. at the Institute of Biochemistry at the University of Oxford, UK. During this time, she discovered her love for Adhesion GPCRs and started delineating the molecular mechanisms of the Adhesion GPCR Latrophilin-1.

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.yo&a

Gunnar Schulte is a Professor in receptor pharmacology and research group leader for the section Receptor Biology and Signaling at the Department of Physiology and Pharmacology. He has a background in biochemistry from the Free University in Berlin/Germany and a Ph.D. in molecular pharmacology (supervisor: Bertil B Fredholm; 1998-2002) from Karolinska Institutet. As a postdoc, he trained first with Ernest Arenas (Karolinska Institutet, Molecular Neurobiology; 2003-2005) and later with Roger J Summers (Monash University, Melbourne Australia, GPCR pharmacology; 2006) before starting his independent research team "Receptor Biology & Signalling" in 2008. Gunnar Schulte is also the scientific secretary of the Swedish Society for Medical Research (SSMF) and a member of the editorial board/editorial advisory board of Molecular Pharmacology, British Journal of Pharmacology, Pharmacological Reviews, and The Journal of Biological Chemistry.

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

''Ralf Jockers studied in Cologne and received a Ph.D. in biotechnology and biochemistry from the University of Braunschweig, Germany. For postdoctoral training, he joined the laboratory of Dr. AD Strosberg in France, where he worked on the regulation of ß-adrenergic receptors. He is the Research director at INSERM with a specific interest in G protein-coupled receptors by developing original BRET and TR-FRET assays. His laboratory is currently located at the Institute Cochin – Inserm (Paris, France).

He was the director of the French network of GPCRs (GDR-3545), currently directs the International Research Network (IRN) i-GPCRnet of the CNRS, is chair of IUPHAR « Melatonin receptor » sub-committee, Editor-in-Chief of « Frontiers in Cellular Endocrinology » and AE of « J Pineal Research”. He is a highly cited researcher – 2019 and 2020 identified by Clarivate Web of Science ™.''

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

Steve Foord trained as a Physiologist and Pharmacologist and worked for Glaxo through to GSK from 1986 to 2008. He introduced molecular pharmacology to a wide range of the companies GPCR projects and was able to initiate some projects. These included the identification of RAMPs (solving some CGRP family issues) and the GABA B, carboxylic and nicotinic acid receptors. He also discovered and championed a novel prostaglandin EP4 drug candidate to development. He finished his career as Head of Bioinformatics for Neuroscience and working on GSKs novel genetics initiative

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

Randy Hall, Ph.D., is a Professor of Pharmacology and Chemical Biology in the Emory University School of Medicine.  Randy received his Bachelor's degree in 1990 from the University of New Hampshire and attended graduate school at the University of California at Irvine, studying the regulation of ionotropic glutamate receptors under the direction of Gary Lynch.  After obtaining his Ph.D. in 1994, Randy moved to the Vollum Institute in Portland, Oregon, to do a post-doctoral fellowship in the laboratory of Thomas Soderling studying glutamate receptor trafficking and phosphorylation.

In 1996, Randy continued his post-doctoral training at Duke University, where he studied the regulation of adrenergic receptors in the laboratory of Nobel Laureate Robert Lefkowitz.  Randy then joined the faculty at the Emory University School of Medicine in 1999.  Over the past two decades, his lab has published numerous groundbreaking findings shedding light on the signaling and regulation of GPCRs from the adrenergic, purinergic, glutamatergic, GABAergic, and adhesion sub-families.  Most recently, his lab has made a number of seminal contributions to understanding the signaling, regulation and in vivo actions of the neuroprotective receptors GPR37 & GPR37L1 as well as the adhesion GPCRs BAI1, BAI2, and GPR56.  Randy’s lab has a special interest in studying disease-associated mutations to human GPCRs that perturb receptor signaling and/or trafficking.

Visit the podcast page to read more about Randy.

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/