🚨 New trial alert! In youth with type 1 diabetes, adding #SGLT2i 💊 (dapagliflozin) to insulin:

✅ Reduced glomerular hyperfiltration

✅ Lowered HbA1c 📉

✅ Boosted time-in-range ⏱️

😌 Safe with DKA precautions in place

📄 #ATTEMPTTrial | @NatureMedicine

🔗 https://doi.org/10.1038/s41591-025-03723-6

📉 New study alert!

Patients with diabetes using GLP-1 receptor agonists had 2x higher risk of developing neovascular macular degeneration 😮

Longer use = greater risk 📈

Clinicians, keep an 👀 on ocular safety!

#GLP1 #Diabetes #EyeHealth #nAMD #JAMAOphthalmology

🧲 New twist in sex determination!

Maternal iron levels shape whether XY embryos become male 🧬👶.

Low iron ➡️ silenced Sry gene ➡️ female development 💡🧪.

Epigenetics meets nutrition in utero—stay iron-clad, moms!

#Epigenetics #IronMatters #SexDetermination

🔬 New in @ScienceMagazine:

Researchers grew mini human organs (gastruloids) with real blood vessels! ❤️🧠

Using stem cells + special cocktails, they modeled early heart & liver development in a dish.

A leap for organoids & regenerative medicine! 🧪🧬 #Biotech #StemCells #Organoids

🧬 Is taurine the secret to youth? Not quite.

📈 New study shows taurine levels 📈 with age—especially in women.

🙅‍♂️ Not a reliable aging biomarker: too much variability, too many mixed signals.

🧠 Context matters. Supplement wisely. #Longevity #AgingResearch #Taurine #Science 🧪

🧬 New vascular villain? It's not always clots.

💥 Necroptosis of endothelial cells triggers red blood cell rupture.

🩸 Sticky RBC fragments form "endo-seals" that block blood flow—especially in COVID-19, stroke, and MI.

🎯 Targets? Think MLKL & complement, not just platelets.

#MedTwitter #COVID19 #VascularBiology #Pathology

🧬 New study reveals 4 stable #Immunotypes in healthy adults!

Each with unique 🔥inflammatory, 🦠CMV-driven, 💧quiet, or 🔥aging-linked immune traits.

They predict LPS response better than age or sex.

Welcome to the era of immune fingerprinting! 🧪🧠

#PrecisionMedicine #Immunology #Multiomics

🥖 Not all carbs are created equal — or digested the same!

A new study shows glycemic responses vary wildly by individual 🍚🥔🍞🍇

Your microbiome, metabolism, and ethnicity all matter!

Precision nutrition is the future 🔬🧬📊

#GlycemicResponse #CGM #NutritionScience #T2D 🍽️

🧬 A new epigenetic clock predicts your functional age — not just birthdays!

🕰️ Built from 91 CpGs, the IC Clock outperforms GrimAge & others at predicting mortality

💪 Linked to T-cell health, 🫁 lung function & 🐟 omega-3 intake

📖 Nature Aging: https://doi.org/10.1038/s43587-025-00883-5

#Aging #Epigenetics #Longevity #Immunosenescence Doximity

🥜 Daily almonds = big wins for metabolic health!

✅ ↓ LDL & total cholesterol

✅ ↑ Vitamin E (α-tocopherol)

✅ ↓ Gut inflammation (calprotectin, MPO)

❌ No change in systemic inflammation or weight

Crunch wisely, live heart-smart! ❤️🧠 #Nutrition #MetabolicSyndrome #RCT #Almonds #GutHealth