Dr RR Baliga's "Got Knowledge Doc" Podkast

Heart attacks & strokes are down, but guess what's rising?

⚡ Atrial fibrillation, 🫀 valve disease, & 🩸 VTE are taking the lead!

It's time to rethink prevention: from plaque to pulse to prognosis.

🧠💊📊 #CardioTwitter #HeartHealth #TheLancet

https://doi.org/10.1016/S0140-6736(25)00990-0

🧠🍬 New study in Nature reveals: High-fructose exposure in early life impairs brain development by suppressing microglial phagocytosis via GLUT5 ➡️ HK2-driven metabolic rewiring.

Result? 🐭 develop anxiety-like behavior.

Cut the sweet talk. Think before you drink. #NeuroScience #FructoseFacts #MentalHealth 🧪🍼

🚨 New 2025 ACC Statement!

Obesity worsens heart failure—but weight loss changes the game.

🏃‍♂️ Lifestyle helps.

💊 Semaglutide & tirzepatide show promise in HFpEF.

🔬 Rethink BMI.

⚖️ Precision + empathy = better outcomes.

👇 Dive into key takeaways.

#CardioTwitter #Obesity #HeartFailure

👵🍽️ Malnutrition in aging isn't just about food — it's frailty, forgetfulness, and function.

The DoMAP model 🧠🔺 reveals how low intake, high needs, and poor absorption collide with social, physical & mental challenges.

Let's fix the hidden hunger. 🥣❤️ #Geriatrics #Malnutrition #HealthyAging

🚨 New BMJ meta-analysis!

After PCI & stopping DAPT, P2Y12 inhibitor monotherapy 💊 reduces MACCE 🧠❤️ (HR 0.77) vs aspirin — without more major bleeding 💉

🫀 MI & stroke ↓

📊 16,117 pts, 5 trials

🧠 Smarter post-PCI strategy?

#CardioTwitter #BMJ #PCI #P2Y12 #Aspirin 🚫

🧬 New study in Aging Cell finds immune resilience—anchored by TCF7 expression—confers a 🚀 15.5-year survival advantage!

💥 SAS-1 high / MAS-1 low = 🔑 to longevity

👵 Midlife is the window.

🧠 Age is biology, but resilience is destiny.

#Longevity #Aging #Immunology #TCF7

🫀 Cardiovascular breakthroughs abound—yet millions still die needlessly.

🌍 Innovation without equity is like a heart without a pulse.

💡 From molecules to communities, it's time to turn science into survival. #GlobalHealth #CardioCare #EquityMatters

🚨New insights from the PRODROME trial!

💊 Ubrogepant 100mg, given before the migraine hits, reduced photophobia, fatigue & brain fog—within hours!

🧠 Targets the prodrome, not just the pain.

📈 A paradigm shift in migraine care?

#Migraine #CGRP #NeuroTwitter N

🔗 https://doi.org/10.1038/s41591-025-03679-7

💊 Big win for kidneys! In the CONFIDENCE trial, combo therapy with #Finerenone + #Empagliflozin 📉 slashed albuminuria 29–32% more than either alone in CKD + T2D patients 🧪🛡️

Safe, fast, and promising! 👥⏱️✅

#Nephrology #CardioRenal #SGLT2i #NEJM 🧬🩺

👁️✨ Scientists have restored infrared vision using tellurium #nanowires implanted in the retina!

🧪 Mice and primates regained light sensitivity and behavioral vision.

🚀 A bold leap toward restoring sight without bulky tech.

#VisionScience #NeuroTech #Retina #Innovation