Dr RR Baliga's "Got Knowledge Doc" Podkast

🥖 Not all carbs are created equal — or digested the same!

A new study shows glycemic responses vary wildly by individual 🍚🥔🍞🍇

Your microbiome, metabolism, and ethnicity all matter!

Precision nutrition is the future 🔬🧬📊

#GlycemicResponse #CGM #NutritionScience #T2D 🍽️

🧬 A new epigenetic clock predicts your functional age — not just birthdays!

🕰️ Built from 91 CpGs, the IC Clock outperforms GrimAge & others at predicting mortality

💪 Linked to T-cell health, 🫁 lung function & 🐟 omega-3 intake

📖 Nature Aging: https://doi.org/10.1038/s43587-025-00883-5

#Aging #Epigenetics #Longevity #Immunosenescence Doximity

🥜 Daily almonds = big wins for metabolic health!

✅ ↓ LDL & total cholesterol

✅ ↑ Vitamin E (α-tocopherol)

✅ ↓ Gut inflammation (calprotectin, MPO)

❌ No change in systemic inflammation or weight

Crunch wisely, live heart-smart! ❤️🧠 #Nutrition #MetabolicSyndrome #RCT #Almonds #GutHealth

🧪 Can we turn back the clock? A new RCT shows TPE + IVIG reversed biological age by 2.6 years in older adults! 🔄🧬

✅ Boosted naïve T cells

⚠️ Small sample, no clinical endpoints

🔍 Personalized markers predict response

#Aging #LongevityScience #Epigenetics 🧓📉✨

🥗 New study in Nature Food: Greater diversity of flavonoid intake—not just quantity—linked to ↓ risk of death, diabetes, heart disease & more 🌈🍇🍵

Eat the rainbow daily: apples, tea, berries, citrus, greens = longevity boost 💪🧬

#Nutrition #Longevity #Flavonoids

Marcus Aurelius (121–180 CE), a Roman emperor and prominent Stoic philosopher, ruled from 161 to 180 CE.

As the last of the Five Good Emperors, his reign marked the end of the Pax Romana, a period of relative peace in the Roman Empire.

Known for his military campaigns against Parthians and Germanic tribes, he also endured the devastating Antonine Plague.

His philosophical reflections, compiled in Meditations, offer insight into Stoic ethics and personal leadership.

Marcus was succeeded by his son Commodus, whose rule marked a decline in Rome's stability. His legacy endures in both historical and philosophical contexts.

🩸 New JCI study reveals how RBC-derived EVs 🧬 in #Type2Diabetes sneak into endothelial cells 🧫, delivering arginase-1 & sparking oxidative stress 🔥—a hidden cause of vascular dysfunction.

Blocking EV uptake = 💡 new therapy?

📖 https://doi.org/10.1172/JCI180900

#CardioTwitter #Diabetes #VascularBiology

Big shift in Alzheimer's care!

We can now predict it years in advance using 🩸 biomarkers like p-tau217, 🧬 genetic risk, & 🤖 AI-analyzed retina scans.

Prevention = lifestyle 🥦🏃‍♂️💤, vaccines 💉, & maybe GLP-1s 💊.

Why wait to treat when you can PREVENT? 🔍

#Alzheimers #PrecisionMedicine #AI

🧬 Did you know your blood cell metabolism could fuel heart disease?

🔁 Disrupted haematometabolism = more inflammation, less cleanup

🧹 Efferocytosis fails → plaques grow

🧠 Aging + CHIP mutations = 🔥 risk

🥗 Fix it with fasting, fitness & future therapies!

#CardioTwitter #MedEd #Haematometabolism ❤️

🧬 The microbiome is medicine's next frontier!

From Fecal Transplants 💩 to probiotics 🦠, diagnostics 🔍 to designer bugs 🧪—we're decoding disease, predicting treatment, and redefining care.

But challenges remain.

🎙️ Dive into the FAQs with Got Knowledge Doc! #Microbiome #GutHealth #MedTwitter 🚀