In this episode we start off with a quick general science news roundup before discussing two new papers in stem cell research. Both papers appeared in the journal Nature. The first describes a novel method of reprogramming somatic cells into induced pluripotent stem cells in vivo, and other describes a method to make a mini cerebral cortex from human embryonic stem cells. The senior author on the latter study, Dr. Juergen Knoblich, joins us to discuss this paper and its implications.