Dr. Todd McDevitt is a Senior Investigator at the Gladstone Institutes. He is also Program Director of the University of California, San Francisco’s Bioengineering Graduate Program (joint with UC Berkeley), and a Professor at UCSF’s Department of Bioengineering and Therapeutic Sciences. His research focuses on engineering 3D, multicellular systems that can be used to study principles of stem cell and developmental biology.

Improving Stem Cell Therapy for Spinal Cord Injury – Researchers have found that modulating the microenvironment of neurons after a spinal cord injury can improve the efficacy of neural progenitor cell grafts.

Brain Organoids Reveal Glioblastoma Origins – Scientists have created a glioblastoma tumor cell atlas that demonstrates heterogeneity, and used cortical organoids to model tumor invasion.

Single-Cell Profiling of the Human Heart – Investigators analyzed cells from normal, failed, and partially recovered human hearts at single cell resolution to better understand the cellular composition and interactions of the adult human heart.

Engineering Chamber-Specific Heart Models – Clinically relevant engineered heart tissues were generated from hPSCs, and were successful in modeling cardiac disease.

Photo Reference: Courtesy of Dr. Todd McDevitt

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