Dr. Valentina Greco is the Carolyn Slayman Professor of Genetics at Yale University. Her lab has developed novel live imaging approaches to track and manipulate stem cells in live animals, allowing them to study the complex orchestration of tissue regeneration using the skin as a model system. She is also a fierce advocate for inclusivity in the scientific community.

Reducing Cell-to-Cell Contact Helps Heart Cell Proliferation – Researchers were able to induce massive expansion of hiPSC-derived cardiomyocytes by activating Wnt and reducing cell-cell contact.

Growing Liver Vasculature from Stem Cells – Scientists have developed a strategy to generate liver sinusoidal endothelial cells from human PSCs by first optimizing arteriovenous specification.

A Role For Sex Hormones in Stem Cell Control – A steroid hormone produced by the ovaries in Drosophila has been shown to stimulate intestinal stem cell growth, which may help with reproduction but cause gut dysfunction.

Beneficial Bioartificial Livers – Investigators have developed a bioartificial liver system that expands liver progenitor-like cells from human primary hepatocytes. The treatment was able to relieve acute liver failure in pigs.

Photo Reference: Courtesy of Dr. Valentina Greco

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