Dr. Henner Farin is a Young Investigator in the German Cancer Consortium, and a Junior Research Group Leader at the Georg-Speyer-Haus Institute for Tumor Biology and Experimental Therapy. His group uses organoids to study cell signaling in intestinal stem cells and colorectal cancer.

Immune Evading Organoids to Treat Type 1 Diabetes – Human islet-like organoids have been created that are glucose responsive, avoid immune detection, and restore glucose homeostasis in diabetic mice.

Regenerating Cartilage in the Joints – By causing slight injury to the joint tissue, scientists were able to stimulate regeneration and growth of local skeletal stem cells in healthy and osteoarthritic mice.

iPSC Model to Study Congenital Heart Disease – A human iPSC model of hypoplastic left heart syndrome was generated to investigate the abnormalities that disrupt healthy heart formation, and identify a therapeutic target.

Modulating Wnt to Support Organoid Growth – Researchers have designed next-generation surrogate Wnts that support long-term expansion of multiple types of organoids.

Photo Reference: Courtesy of Dr. Henner Farin

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