Dr. Miki Ebisuya is a Group Leader at the European Molecular Biology Laboratory in Barcelona. Her lab focuses on synthetic developmental biology, where they reconstitute developmental mechanisms by making artificial gene circuits, and study interspecies differences by comparing organoids of different animals.

Lab-Grown Tissue Grafts for Personalized Joint Replacement – Autologous fat-derived cells have been used to engineer cartilage-bone grafts that regenerated and repaired a jaw joint in a minipig model.

SARS-CoV-2 Infection in the Brain – Using brain organoids, researchers have found that SARS-CoV-2 infects choroid plexus cells, but not neurons or glia. This infection damages the epithelium, leading to leakage.

The Healing Power of Extracellular Vesicles – Using a heart-on-chip model, investigators have found that endothelial cell-derived extracellular vesicles contain cardioprotective proteins that rescue ischemia-reperfusion injury.

How Plant Stem Cells Resist Infection – The meristem, the collection of stem cells that builds plants, is resistant to viral infection. Scientists have identified a transcription factor that triggers innate antiviral immunity in the meristem of Arabidopsis.

Photo Reference: Courtesy of Dr. Miki Ebisuya

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