Dr. Thomas Zwaka is the Director of the Huffington Center for Cell-Based Research in Parkinson’s Disease and a Professor of Regenerative and Developmental Biology at the Icahn School of Medicine at Mount Sinai. His research focuses on fundamental questions surrounding stem cell biology, including how to reverse the process of differentiation and “re-program” any given cell type into a pluripotent stem cell. He talks about his lab’s work using bat iPSCs to study viruses.

A New Base Editing Technology – Scientists have developed a novel adenine transversion editor capable of efficient A·T-to-C·G base editing.

Exploring Hypertrophic Cardiomyopathy – Researchers investigated the genotype-phenotype relationship in siblings with a family history of hypertrophic cardiomyopathy.

A Preclinical Model for Parkinson’s Disease – A new optogenetic method induces α-syn aggregates in Parkinson’s disease neurons and organoids.

A Stem Cell Zoo – Scientists have recapitulated the segmentation clock of six mammals using PSCs.

Photo Reference: Courtesy of Thomas Zwaka

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