Dr. Nathaniel Huebsch is an Assistant Professor of Biomedical Engineering at Washington University in St. Louis. His lab focuses on understanding how mechanical cues originating at cell-cell and cell-extracellular matrix contacts influence signaling and fate. They are especially interested in how those cues affect heart development and disease. He talks about cardiac models and cardiomyocyte maturity.

Modeling Early Development – Peri-gastruloids model human post-implantation development into early organogenesis.

Fatty Acid Synthesis in Endoderm Differentiation – Researchers identified a fatty acid synthesis/oxidation shift during early differentiation.

Editing HSCs In Vivo – Scientists designed a strategy to reprogram bone marrow stem cells directly within the body without the need for donor cells or the use of potentially toxic conditioning regimens.

T Cell Therapy for Solid Tumors – Gavo-cel is an engineered T cell therapy tested in patients with mesothelin-expressing solid tumors.

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