Dr. Jose Polo is a Professor of Epigenetics and the Director of the Centre for Epigenetics at the University of Adelaide. He is also a Professor in the Department of Anatomy and Developmental Biology at Monash University. His lab studies the transcriptional and epigenetic mechanisms that govern cell identity. He talks about his team’s work on cell fate, iBlastoids, and placental models for SARS-CoV-2.

Norepinephrine Neurons – Researchers generated locus coeruleus norepinephrine neurons from human pluripotent stem cells, enabling the investigation of their roles in psychiatric and neurodegenerative diseases.

Mice with Rat Hearts – Intraspecies blastocyst complementation generated a functional cardiovascular system in mice.

Cancer Risk in Gene Therapy – Scientists identified genetic drivers that could increase leukemia risk in gene therapy trials for sickle cell disease.

Photo Reference: Courtesy of Dr. Jose Polo

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