Dr. Shukry Habib is an Associate Professor in the Department of Biomedical Sciences at the Université de Lausanne. His lab works at the intersection of stem cell biology, biophysics, and tissue engineering to investigate how tissues form. He talks about developing a transplantable bandage for bone repair and the role of Wnt signaling and cytonemes in development.

Unequal Blastomere Contribution – Prospective lineage tracing of human embryos revealed that the majority of the epiblast is derived from only one 2-cell stage blastomere.

Epigenetic Reprogramming of Germ Cells – Epigenetic reprogramming resets parental epigenetic memories and differentiates primordial germ cells into mitotic pro-spermatogonia or oogonia.

Blood-Brain Barrier Organoids – Researchers used patient-derived blood-brain barrier assembloids to model cerebral cavernous malformations.

Treating Genetic Liver Disease –  A new study combines ex vivo large-scale cell expansion and gene editing in patient-derived transplantable hepatocytes, which holds potential for treating human liver diseases.

Image courtesy of Dr. Shukry Habib

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