Dr. Valentina Greco is the Carolyn Walch Slayman Professor of Genetics and Co-Chair of the Committee on the Status of Women in Medicine at Yale University. Her research focuses on tissue homeostasis in the face of continuous cellular turnover, frequent injuries, and spontaneous mutations. She talks about her research on skin and hair follicle stem cells, the role of imaging techniques, and bridging science and art. She also discusses disease modeling and building an inclusive lab culture.

Next-Generation Genome Editing – An RNA-guided recombinase enzyme enables the insertion, excision, or inversion of specific target DNA sequences.

Maintaining HSC Function – Researchers identified the transcription factor Nynrin as a crucial regulator of HSC maintenance by modulating mitochondrial function.

A Vascularized Heart-on-a-Chip – Primitive macrophages enhanced cardiac tissue functionality.

Brain Chimeroids – A new multidonor human brain cortical organoid model was generated by co-developing cells from a panel of individual donors in a single organoid.

Image courtesy of Dr. Valentina Greco

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