Mindrolling with Raghu Markus

Ep. 597 – Breaking the Boundaries of Compassion with Duncan Trussell


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From psychedelic breakthroughs to breaking the boundaries of compassion, Duncan Trussell and Raghu Markus offer unfiltered wisdom on the messy magic of waking up.

Take the opportunity to support Ram Dass’ Love Serve Remember Foundation and step into another dimension with a one-of-a-kind pair of custom Midnight Gospel sneakers. Hand-crafted by The Shoe Surgeon to replicate the iconic shoes worn by Clancy himself in the groundbreaking animated series by Duncan Trussell and Pendleton Ward.

All proceeds benefit the Love Serve Remember Foundation and their work to preserve and continue the teachings of Neem Karoli Baba and Ram Dass. CLICK HERE to bid on the shoes and find more exciting one-of-a-kind collector’s items at the LSRF Auction HERE.

This time on Mindrolling, Duncan and Raghu connect over:

  •  The Good Friday psychedelic experiment 
  • New MDMA research with octopuses and insights into social neuroscience
  • Brain scans of Tibetan monks practicing loving-kindness (Metta) meditation
  • ‘Making the most’ of the neuroplasticity that can occur during a psychedelic experience 
  • The most powerful issue we have to deal with: identity 
  • Transactional compassion versus offering genuine love and care to all 
  • Reversing our own neurosis and breaking through the self-created boundaries of compassion
  • Embracing spiritual discipline through the daily grind of practice
  • Moving through what the Buddhists call ‘the original heart of sadness’ 
  • Maladaptive behaviors that we develop to mask the pain of humanity 
  • Alcohol as the west’s faulty ‘ayahuasca’ and initiation practice 
  • Self-compassion and allowing ourselves to be human

Today's episode is sponsored by Psychedelic Science 2025 & Reunion:

Join the most important psychedelic gathering of the year......bridging science, spirit & society at Psychedelic Science 2025: THE INTEGRATION, hosted by the Multidisciplinary Association for Psychedelic Studies. Be part of the movement that will shape the next era of mental health, medicine, and consciousness.

Featuring speakers like Paul Stamets, United States Representative Tim Ryan, Rick Doblin, founder of Internal Family Systems (IFS) Richard Schwartz, Pilar Guzman, CEO/Medical Director of the APA Marketa M. Wills, Raghu Markus, comedian Reggie Watts, musicians TYCHO & Jim James, and many more!

Listeners get 15% off tickets to the 5-day event with our promo code LSRF15 at PsychedelicScience.org

Mindrolling is brought to you by Reunion. Reunion is offering $250 off any stay to the Love, Serve, Remember community. Simply use the code “BeHere250” when booking. Disconnect from the world so you can reconnect with yourself at Reunion.  Hotel | www.reunionhotelandwellness.com Retreats | www.reunionexperience.org

About Duncan Trussell:

Duncan Trussell is a stand-up comedian, podcaster, and actor. His popular podcast, The Duncan Trussell Family Hour, has been downloaded over 25 million times and is known for its blend of humor, fringe ideas, eclectic guests, and great interviews. The DTFH is the foundation for Duncan’s Netflix animated series, The Midnight Gospel, which he co-created with Pendleton Ward in 2020. To learn more about Duncan’s work, visit his website at duncantrussell.com.

“What do you do when you're passing strangers in the street and you love them completely? It's not bullshit. You feel about them the way you feel about someone you love, like your mother. What happens when the boundary of compassion breaks through and there is no longer this person deserves compassion, this person doesn't. It's like a dam broke." – Duncan Trussell

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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