In this episode, we break down one of the most talked-about (and misunderstood) topics in functional medicine: methylation and the COMT gene.

What does it really mean to have a methylation gene variant? How common is it? And what’s the difference between being a “warrior” vs a “worrier”?

We dive into:

🧬 What methylation is and why it matters for brain chemistry, hormones, detoxification, and cardiovascular health
📊 The likelihood of Americans carrying some form of methylation-related gene variant
🧠 What the COMT gene does when it’s functioning properly (dopamine, estrogen, stress response)
⚖️ The three COMT variants — Val/Val, Val/Met, Met/Met — and how they influence personality, stress tolerance, and focus
🔥 “Warrior vs Worrier” explained
⚠️ Symptoms associated with slower or faster COMT activity
🧪 How to test (genetic testing, bloodwork, organic acid testing)
💊 What you can actually do about it — lifestyle, stress management, targeted supplementation, and methylation support

If you’ve struggled with anxiety, brain fog, hormone imbalances, poor stress tolerance, or feeling “wired but tired,” this episode will help you understand how your genetics may be influencing your physiology — and more importantly, what you can do to support it.

Remember: genes load the gun, but lifestyle pulls the trigger. Having a variant does NOT mean you’re broken — it simply means you may need a more personalized approach.

If you found this helpful, don’t forget to like, subscribe, and share with someone who’s deep in the gene-variant rabbit hole.