Over the past few weeks some really exciting papers came out describing the reprogramming of one cell into another, a process called Direct Reprogramming.  On this episode we talk to Dr. Justin Ichida from the University of Southern California who uses the latest reprogramming techniques in his lab to study neural disease. His current research is focused on using patient-specific disease models to define the mechanisms that lead to neuronal loss in ALS and frontotemporal dementia.

University of Southern California – The Ichida Lab – Board California Institute for Regenerative Medicine (CIRM) Center for Regenerative Medicine and Stem Cell Research

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Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages

Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes

Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming

Photo Reference: Courtesy of Dr. Justin Ichida

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