A look at one of the most common and potentially concerning upper respiratory infections in children.
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Tags: Airway, Infectious Diseases, Pediatrics
Show Notes
Croup is a viral infection starts in the nasal and pharyngeal mucosa but spreads to the larynx and tracheaSubglottic narrowing from inflammationDynamic obstructionBarking coughInspiratory stridorCauses:Parainfluenza virus (most common)RhinovirusEnterovirusRSVRarely: Influenza, MeaslesAge range: 6 months to 36 monthsSeasonal component with high prevalence in fall and early winterDifferentialBacterial tracheitisAcute epiglottitisInhaled FBRetropharyngeal abscessAnaphylaxisClassically a prodrome of nonspecific symptoms for 1-3 days with low grade fevers, congestion, runny nose.Symptoms reach peak severity on the 4th day“Steeple sign” on Xray (subglottic narrowing) present in only 50% of patients with croupAssess air entry, skin color, level of consciousness, for tachypnea, if there are retractions / nasal flaring (if present at rest or with agitation) & coughing“Westley Croup Score” (https://www.mdcalc.com/westley-croup-score)Chest wall retractionsStridorCyanosisLevel of consciousnessAir entryMild CroupOccasional barking cough, but no stridor at rest and mild to no retractionsTx: Single dose of dexHas been shown to improve severity and duration of symptomsRoute is not particularly important, whether it’s PO, IV or IMChosen route should aim to minimize agitation in the patient that might worsen their conditionMay be managed at with supportive careHumidifiers (NB: there isn’t good evidence supporting the use of humidifiers)AntipyreticsPO fluidsModerate GroupMay have stridor at rest, mild-moderate retractions but no AMS and will not be in distress.Tx: Dex + Racemic EpinephrineRacemic epinpehrine will start to work in about 10 minutesEffects last for more than an hourSevere groupReceives the same initial therapy as the moderate group with dex and race epiPts with worrisome signs: stridor at rest, marked retraction, cyanosis and/or lethargyHeliox (a combinations of 70-80% helium + 20-30% oxygen) may be attemptedThere is limited evidence to support the role of heliox in croup,NB: Pt may require higher levels of oxygen than the 20-30% mixture may provideIntubationAnticipate edema narrowing the airwayConsider starting with a tube that is 0.5 to 1 mm smaller than size typically usedPatients without stridor at rest or respiratory distress can be generally discharged from the EDIf epinephrine is given, patients should be monitored for 2-4 hours for reemergence of symptoms as the medication wears offCroup usually affects children within the age range of 6 months to 36 months with the most common cause being parainfluenza virusGiven the symptom overlap, we must consider more concerning diagnoses, including bacterial tracheitis, in these patients, especially if they are ill appearing or traditional therapies are ineffectiveAll patients benefit from a one-time dose of dexamethasone and, if racemic epinephrine is given, the patient should be observed for at least 3 hoursIf intubation is required, anticipate a narrowed airwayParent Article: https://coreem.net/core/croup/ by Dr. Pankow
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