Core EM - Emergency Medicine Podcast

Episode 163.0 – Croup


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A look at one of the most common and potentially concerning upper respiratory infections in children.

Host:

Brian Gilberti, MD

https://media.blubrry.com/coreem/content.blubrry.com/coreem/Croup.mp3
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Tags: Airway, Infectious Diseases, Pediatrics
Show Notes

Background

  • Croup is a viral infection starts in the nasal and pharyngeal mucosa but spreads to the larynx and trachea
    • Subglottic narrowing from inflammation
    • Dynamic obstruction
    • Barking cough
    • Inspiratory stridor
    • Causes:
      • Parainfluenza virus (most common)
      • Rhinovirus
      • Enterovirus
      • RSV
      • Rarely: Influenza, Measles
      • Age range: 6 months to 36 months
      • Seasonal component with high prevalence in fall and early winter
      • Differential
        • Bacterial tracheitis
        • Acute epiglottitis
        • Inhaled FB
        • Retropharyngeal abscess
        • Anaphylaxis
        • Presentation & Diagnosis

          • Classically a prodrome of nonspecific symptoms for 1-3 days with low grade fevers, congestion, runny nose.
          • Symptoms reach peak severity on the 4th day
          • “Steeple sign” on Xray (subglottic narrowing) present in only 50% of patients with croup
          • Assess air entry, skin color, level of consciousness, for tachypnea, if there are retractions / nasal flaring (if present at rest or with agitation) & coughing
          • “Westley Croup Score” (https://www.mdcalc.com/westley-croup-score)
            • Chest wall retractions
            • Stridor
            • Cyanosis
            • Level of consciousness
            • Air entry
            • Management

              • Mild Croup
                • Occasional barking cough, but no stridor at rest and mild to no retractions
                • Tx: Single dose of dex
                  • Has been shown to improve severity and duration of symptoms
                  • Route is not particularly important, whether it’s PO, IV or IM
                  • Chosen route should aim to minimize agitation in the patient that might worsen their condition
                  • May be managed at with supportive care
                    • Humidifiers (NB: there isn’t good evidence supporting the use of humidifiers)
                    • Antipyretics
                    • PO fluids
                    • Moderate Group
                      • May have stridor at rest, mild-moderate retractions but no AMS and will not be in distress.
                      • Tx: Dex + Racemic Epinephrine
                        • Racemic epinpehrine will start to work in about 10 minutes
                        • Effects last for more than an hour
                        • Severe group
                          • Receives the same initial therapy as the moderate group with dex and race epi
                          • Pts with worrisome signs: stridor at rest, marked retraction, cyanosis and/or lethargy
                          • Heliox (a combinations of 70-80% helium + 20-30% oxygen) may be attempted
                            • There is limited evidence to support the role of heliox in croup,
                            • NB: Pt may require higher levels of oxygen than the 20-30% mixture may provide
                            • Intubation
                              • Anticipate edema narrowing the airway
                              • Consider starting with a tube that is 0.5 to 1 mm smaller than size typically used
                              • Disposition:

                                • Patients without stridor at rest or respiratory distress can be generally discharged from the ED
                                • If epinephrine is given, patients should be monitored for 2-4 hours for reemergence of symptoms as the medication wears off
                                • Take Home Points

                                  • Croup usually affects children within the age range of 6 months to 36 months with the most common cause being parainfluenza virus
                                  • Given the symptom overlap, we must consider more concerning diagnoses, including bacterial tracheitis, in these patients, especially if they are ill appearing or traditional therapies are ineffective
                                  • All patients benefit from a one-time dose of dexamethasone and, if racemic epinephrine is given, the patient should be observed for at least 3 hours
                                  • If intubation is required, anticipate a narrowed airway
                                  •  

                                    Parent Article: https://coreem.net/core/croup/ by Dr. Pankow


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