Kate, Mark, Gary and Henry discuss 4 important new studies relevant to primary care clinicians: negative pressure wound therapy for wounds healing by secondary intention, comparative effectiveness of acute migraine treatments, contrast enhanced mammography, US, or MRI for women with dense breasts, and metformin for knee pain in patients without diabetes.

Negative pressure wound therapy: https://pubmed.ncbi.nlm.nih.gov/40250455/

Acute migraine treatments: https://pubmed.ncbi.nlm.nih.gov/40096693/

Best enhanced screening for women with dense breasts:  https://pubmed.ncbi.nlm.nih.gov/40412427/

Metformin for knee pain in patients without DM: https://pubmed.ncbi.nlm.nih.gov/40274279/