Join Kate, Mark, Gary and Henry as they discuss 4 great new POEMs (studies with the potential to change practice): a digital mental health intervention, the risk of DKA in patients using SGLT2 inhibitors, esketamine’s effects on suicidal ideation and unresponsive depression, and whether “one-size-fits-all” thyroid reference ranges misleading.

Links:

Essential Evidence Plus: www.essentialevidenceplus.com

Digital mental health app for depression: https://pubmed.ncbi.nlm.nih.gov/40227715/

RIsk of DKA with SGLT2s: pubmed.ncbi.nlm.nih.gov/40070044/

Esketamine and resistant depression or suicidality: pubmed.ncbi.nlm.nih.gov/39790081/

What is a normal TSH: https://pubmed.ncbi.nlm.nih.gov/40324200/

Joseph O'Connor and the Escape Line Trilogy (2 great novels): https://www.amazon.com/The-Rome-Escape-Line-Trilogy-2-book-series/dp/B0BSNX3C89