In Part 2 of this "Mini Grand Rounds" series, we discuss important side effects of ATII including thrombosis, especially in the setting of COVID.

References:

Celi A, Cianchetti S, Dell’Omo G, Pedrinelli R. Angiotensin II, tissue factor and the thrombotic paradox of hypertension. Expert Review Cardiovasc Therapy. 2010. 8 (12)

Senchenkova EY, Russell J, Almeida-Paula LD, et al. Angiotensin II-mediated microvascular thrombosis. Hypertension. 2010; 56 (6): 1089-1095

Zhang P, Zhu L, Cai J, et al. Association of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19. Circ Res. 2020: 126 (12): 1671-1681

Tralhao A, Moita LF, Povoa P. Potential benefits of angiotensin II in COVID-19 patients: beyond reasonable doubt? Crit Care. 2020; 243 (324)

Zangrillo A, Landoni G, Beretta L, et al. Angiotensin II infusion in COVID-19-associated vasodilatory shock: a case series. Crit Care. 2020; 24: 227

Want H, Das S, Wieruszewski PM, et al. Unexpected BP sensitivity to angiotensin II in a patient with coronavirus disease 19, ARDS, and septic shock. CHEST. 2020; 158 (2): e55-58

Disclaimer: 
The information contained within the  ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for informational/ educational purposes only, is not meant to replace professional medical judgement, and does not constitute a provider-patient relationship between you and the authors. Information contained herein may be accidentally inaccurate, incomplete, or outdated, and users are to use caution,  seek medical advice from a licensed physician,  and consult available resources prior to any medical decision making. The contributors of the ER-Rx podcast are not affiliated with, nor do they speak on behalf of,  any medical institutions, educational facilities, or other healthcare programs.

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Disclaimer:

The information contained within the ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for informational/ educational purposes only, is not meant to replace professional medical judgement, and does not constitute a provider-patient relationship between you and the authors. Information contained herein may be accidentally inaccurate, incomplete, or outdated, and users are to use caution, seek medical advice from a licensed physician, and consult available resources prior to any medical decision making. The contributors of the ER-Rx podcast are not affiliated with, nor do they speak on behalf of, any medical institutions, educational facilities, or other healthcare programs.