We're witnessing the early stages of a paradigm shift, as artificial intelligence is beginning to impact virtually every aspect of healthcare, from research to patient care. And there's much, much more to come.

This week, Dr. Brad Willingham, the Director of MS Research at Shepherd Center in Atlanta, joins me to discuss how AI will impact MS patient care.

We'll also share the encouraging results from a Phase 2 open-label extension study for Fenebrutinib, an investigational disease-modifying therapy.

We'll tell you about study results that show exercise interventions that follow physical activity guidelines for MS can have a significant impact on MS-related depression.

And we're sharing the results of a study that illustrate what can happen when you delay starting a disease-modifying therapy.

We have a lot to talk about! Are you ready for RealTalk MS??!

This Week: How AI will impact MS patient care :22

Fenebrutinib shows positive results after one-year extension study 1:33

MS-related depression can be significantly eased through exercise intervention that follows physical activity guidelines for MS 3:36

What happens when you delay starting disease-modifying therapy? 8:46

Dr. Brad Willingham discusses how artificial intelligence is impacting all aspects of healthcare 14:29

Share this episode 33:18

Have you downloaded the free RealTalk MS app? 33:38

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LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

Become an MS Activist https://nationalmssociety.org/advocacy

STUDY: Safety and Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (FENopta): A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase 2 Trial and Open-Label Extension https://thelancet.com/journals/laneur/article/PIIS1474-4422(25)00174-7/abstract?rss=yes

STUDY: Effects of Meeting Exercise Guidelines on Depression and Anxiety in Multiple Sclerosis: A Systematic Review and Meta-Analysis https://tandfonline.com/doi/full/10.1080/09593985.2025.2518261

Exercise and Physical Activity Recommendations for ALL People with MS https://nationalmssociety.org/news-and-magazine/news/exercise-and-physical-activity-recommend

STUDY: Delayed Access and Adherence are Real-World Challenges That Compromise Effectiveness of Natalizumab in Multiple Sclerosis https://sciencedirect.com/science/article/abs/pii/S2211034825003694

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RealTalk MS Episode 413 Guest: Dr. Brad Willingham

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