Core EM - Emergency Medicine Podcast

Episode 69.0 – Antibiotics in COPD Exacerbations


Listen Later

This week we discuss why we use antibiotics in COPD exacerbations and whether we should continue to do so.

https://media.blubrry.com/coreem/content.blubrry.com/coreem/Episode_69_0_Final_Cut.m4a
Download
Leave a Comment
Tags: Antibiotics, COPD, COPD Exacerbation, Pulmonary
Show Notes

Take Home Points

  1. Most COPD exacerbations are caused by infectious etiologies. While these can be viral, there’s also a decent chance it was caused by an overgrowth of bacteria that chronically colonize these patients.
  2. Strong evidence from systematic reviews demonstrates that antibiotic use reduces in-hospital mortality and decreases treatment failure
  3. The GOLD group recommends antibiotics be given to patients who have increased dyspnea, increased sputum volume and increased sputum purulence or require non-invasive or invasive ventilation for their exacerbation.
  4. Finally, a short course of antibiotics – either ampicillin, doxycycline or azithromycin is adequate for management.
  5. Read More

    GOLD Reports: Diagnosis, Management and Prevention 2016

    Berg RMG, Plovsing RR. The hardships of being a Sith Lord: implications of the biopsychosocial model in a space opera. Adv Physiol Educ 2016; 40: 234-6. PMID: 27105743

    Johannes M et al. Antibiotics in Addition to Systemic Corticosteroids for Acute Exacerbations of Chronic Obstructive Pulmonary Disease. Am J Resp Crit Care Med 2010; 181(2): 150-7. PMID: 19875685

    Quon BS et al. Contemporary management of acute exacerbations of COPD: a systematic review and metaanalysis. Chest 2008; 133:756-66. PMID: 18321904

    Ram FS et al. Antibiotics for exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2006:CD004403 PMID: 16625602

    Rothberg MB et al. Antibiotic Therapy and Treatment Failure in Patients Hospitalized for Acute Exacerbations of Chronic Obstructive Pulmonary Disease. JAMA 2010; 303(20): 2035-2042 PMID: 20501925

    Vollenweider DJ et al. Antibiotics for exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2012: CD010257 PMID: 23235687

    The Podcasting Course


    Read More
    ...more
    View all episodesView all episodes
    Download on the App Store

    Core EM - Emergency Medicine PodcastBy Core EM

    • 4.5
    • 4.5
    • 4.5
    • 4.5
    • 4.5

    4.5

    237 ratings


    More shows like Core EM - Emergency Medicine Podcast

    View all
    EMCrit FOAM Feed by Scott D. Weingart, MD FCCM

    EMCrit FOAM Feed

    1,864 Listeners

    Emergency Medicine Cases by Dr. Anton Helman

    Emergency Medicine Cases

    539 Listeners

    JAMA Clinical Reviews by JAMA Network

    JAMA Clinical Reviews

    496 Listeners

    The Resus Room by Simon Laing, Rob Fenwick & James Yates

    The Resus Room

    104 Listeners

    EM Clerkship by Zack Olson, MD ; Mike Estephan, MD ; Maddie Watts, MD

    EM Clerkship

    808 Listeners

    The Curbsiders Internal Medicine Podcast by The Curbsiders Internal Medicine Podcast

    The Curbsiders Internal Medicine Podcast

    3,336 Listeners

    Emergency Medical Minute by Emergency Medical Minute

    Emergency Medical Minute

    257 Listeners

    Core IM | Internal Medicine Podcast by Core IM Team

    Core IM | Internal Medicine Podcast

    1,095 Listeners

    The Internet Book of Critical Care Podcast by Adam Thomas & Josh Farkas

    The Internet Book of Critical Care Podcast

    694 Listeners

    The Clinical Problem Solvers by The Clinical Problem Solvers

    The Clinical Problem Solvers

    519 Listeners

    Harrison's PodClass: Internal Medicine Cases and Board Prep by AccessMedicine

    Harrison's PodClass: Internal Medicine Cases and Board Prep

    349 Listeners

    Run the List by Walker Redd, Emily Gutowski, Navin Kumar, Joyce Zhou, Blake Smith

    Run the List

    248 Listeners

    Critical Care Scenarios by Brandon Oto, PA-C, FCCM and Bryan Boling, DNP, ACNP, FCCM

    Critical Care Scenarios

    249 Listeners

    The Curious Clinicians by The Curious Clinicians

    The Curious Clinicians

    366 Listeners

    Critical Care Time by Critical Care Time Podcast

    Critical Care Time

    236 Listeners