In this episode of the RCP Medicine Podcast, Dr Neil Stone, consultant in infectious diseases and microbiology at University College London Hospitals and associate professor at UCL, joins host Dr Rohan Mehra to explore the often overlooked and increasingly important field of clinical mycology.

The conversation covers a wide spectrum of fungal infections—from diagnosing and managing invasive candidiasis to understanding the global emergence of Candida auris, and the clinical complexities of Cryptococcus and Aspergillus infections. Dr Stone also sheds light on dimorphic fungi, discussing their unique biology, geographical distribution, and the diagnostic challenges they present. Beyond individual pathogens, the episode emphasizes the broader environmental and global health implications of fungal disease, highlighting the need for a One Health approach.

Whether you're a clinician, student, or simply curious about the fungal kingdom, this episode is rich with clinical insights, diagnostic tips, and global perspectives on one of medicine’s most challenging and evolving frontiers.

Resources

WHO Antifungals Report 2025 Antifungal agents in clinical and preclinical development: overview and analysis

WHO Antifungal diagnostics report 2025 Landscape analysis of commercially available and pipeline in vitro diagnostics for fungal priority pathogens

WHO Priority Fungal Pathogens list https://www.who.int/publications/i/item/9789240060241

IDSA Aspergillosis Guidelines 2016 https://www.idsociety.org/practice-guideline/aspergillosis/

Global Guideline for Candiasis 2025 Lancet 2025 https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00749-7/fulltext

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Music:

Episode 50 onward - Bensound.com

Episodes 1 - 49 'Impressive Deals' - Nicolai Heidlas