This episode is an audio version of a video interview conducted by the Journal's Editor in Chief, Dr Audiey Kao, with Dr Carla Perissinotto. Dr Perissinotto is an Associate Professor of Medicine at the University of California San Francisco. She joined us to talk about the health consequences of social isolation and loneliness during the COVID-19 pandemic. To watch the full video interview, head to our site, JournalOfEthics.org, or visit our YouTube channel.