Here we explore how data science is revolutionizing our understanding of protein structures, with a special focus on the exciting developments in protein folding and evolution. We’re joined by two experts in the field: Philip Bourne, the founding dean of the UVA School of Data Science, and Cam Mura, a biomolecular data scientist. From new tools like DeepUrfold to the future of biomedical applications, Bourne and Mura provide a unique look into how cutting-edge technology is transforming the world of molecular biology.