The U.S. is in the midst of a loneliness epidemic. And for a lot of people, the feeling is even more pronounced during the holidays. In addition to its emotional impact, chronic loneliness and social isolation have some dramatic health consequences: increased risk of heart disease and stroke, infections, cancer, even premature death. Recent research also suggests that loneliness can change the way people process the world. So today on the show, host Regina G. Barber talks to Rachel Carlson about the neuroscience of loneliness.

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