Fertility and Sterility On Air

In this month's Fertility & Sterility: Unplugged, we take a look at articles from F&S's sister journals! Topics this month include: whether the optimal time interval for trigger varies depending on the trigger medication used (02:36), the mechanisms by which different trigger medications affect final oocyte maturation (16:05), how alcohol alters the blood-testis barrier function (31:10), and an analysis of the TikTok content specific to endometriosis-related infertility (45:15).

F&S Reports: https://www.fertstertreports.org/article/S2666-3341(25)00114-X/fulltext F&S Reviews: https://www.fertstertreviews.org/article/S2666-5719(25)00010-6/fulltext F&S Science: https://www.fertstertscience.org/article/S2666-335X(25)00050-3/fulltext Consider This: https://www.fertstert.org/article/S0015-0282(24)00873-2/fulltext

View the sister journals at:

• https://www.fertstertreviews.org
• https://www.fertstertreports.org
• https://www.fertstertscience.org

Welcome to Fertility & Sterility Roundtable! Each month, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.

This month, we welcome Dr. Lydia Hughes and Dr. Eric Widra to discuss the ethics of egg-sharing, or "split-cycles" for fertility preservation. This is where an egg donor freezes their eggs for their own future use for reduced or no cost in exchange for donating a portion of the cohort.

Dr. Hughes is a second-year REI fellow at Northwestern University in Chicago, where she also completed her residency in Obstetrics and Gynecology. She earned her medical degree from the University of Alabama at Birmingham. Dr. Hughes's clinical and academic interests include reproductive ethics, PCOS, and ovarian aging.

Dr. Widra currently serves as Executive Senior Medical officer and Vice President, Development for Shady Grove Fertility and US Fertility, respectively. He was formerly Chief Medical Officer of SG Fertility, and Associate Director of the Combined Federal Fellowship in Reproductive Endocrinology and Infertility, operated through the NIH, Walter Reed National Military Medical Center and SG Fertility.

View Fertility and Sterility at https://www.fertstert.org/

Fertility & Sterility on Air is at the European Society of Human Reproduction and Embryology 41st Annual Meeting in Paris, France (Part 2)! In this episode, our hosts Kate Devine, Eve Feinberg, and Micah Hill cover:

• Discussing the state of assisted reproductive technology in Brazil with Giuliano Bedoschi (01:01)
• Whole transcriptome and genome sequencing of standard embryo biopsies can potentially reduce failed euploid transfers with Kaylene Ready and Jeremy Grushcow (09:03) The use of AI in ovarian stimulation with Eduardo Hariton (19:45)
• Modeling embryonic adhesion at cellular resolution within a microfluidic endometrium-on-a-chip platform with Sofia Zaragozano (32:33)
• Assessing the ploidy status of atypically fertilised embryos – recovery of embryos for potential clinical use with Sharyn Stock-Myer (40:41)
• Role of micronutrients and probiotics supplementation on reproductive outcomes in an oocyte donation program with Sara Maggi and Silvia Bonta (42:47)
• Male infertility, life expectancy, and long-term health risks: exploring what can sperm reveal about health with Omar Ammar (58:00)
• Mitochondrial DNA 'reversal' is common in children born following meiotic spindle transfer, potentially reducing the efficacy of mitochondrial replacement therapies with Munuse Savash (01:05:57)

View Fertility and Sterility at https://www.fertstert.org/

Fertility & Sterility on Air is at the European Society of Human Reproduction and Embryology 41st Annual Meeting in Paris, France (Part 1)! In this episode, our hosts Kate Devine, Eve Feinberg, and Micah Hill cover:

• outcomes from programmed ovulatory frozen embryo transfer cycles vs. modified natural frozen embryo transfer cycles with Philippos Edimiris (0:56),
• non-invasive preimplantation genetic testing using metabolomics with Sofia Nunes (9:23),
• optimizing timing of modified natural cycle frozen embryo transfer cycles with Amelie Johansen and Kristine Løssl (17:46),
• mechanisms and consequences of ovarian aging with Francesca Duncan (27:18),
• comparing pregnancy loss rates in natural cycle vs. artificial cycle endometrial preparation prior to euploid embryo transfer with Caroline Roelens (38:24),
• and endometrial health and reproductive outcomes with Shari Mackens(49:44).

View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:

04:20 Poor intracytoplasmic sperm injection outcome in infertile males with azoospermia factor c microdeletions

10:17 Patients with a body mass index of ≥45 kg/m2 can safely undergo oocyte retrievals and anticipate similar assisted reproductive technology outcomes

21:26 Increased endometrial thickness up to 12 mm is associated with increased odds of live birth among fresh and frozen-thawed autologous transfers with or without preimplantation genetic testing

34:21 The chorionic bump is a predictor of miscarriage: a retrospective analysis of 13,656 in vitro fertilization pregnancies

47:01 Prospective validation of anti-Müllerian hormone cutoff to determine polycystic ovarian morphology: HARMONIA study

58:21 Effect of glucagon-like peptide 1 agonist medications on weight loss in patients with and without polycystic ovary syndrome

View Fertility and Sterility at https://www.fertstert.org/

Welcome to Fertility & Sterility Roundtable! Each month, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.

This month, we are excited to talk about State Level Advocacy with Elizabeth Carr, the first baby born via IVF in the United States, and Dr. Preston Parry.

Elizabeth Carr is a passionate advocate for fertility rights and access. She has presented to audiences around the globe including at the United Nations, ASRM, ESHRE, and the national infertility association, RESOLVE. She has helped companies craft benefit packages and parental leave policies. Her professional experience in the field of journalism, marketing and events, and fundraising. She enjoys marathons and is a writer when not advocating.

Dr. Preston Parry completed residency in Ob/Gyn at Tufts and went south to Louisville for his fellowship in Reproductive Endocrinology and Infertility. He was in academic REI for 8 years, including as division chief, before opening his own practice, Positive Steps Fertility, in 2017. He is a past president of the Society of Reproductive Surgeons and is currently the chair of ACOG Mississippi. He also is on the Editorial Board of Fertility and Sterility.

View Fertility and Sterility at https://www.fertstert.org/

In this month's Fertility & Sterility: Unplugged, we take a look at articles from F&S's sister journals! Topics this month include: impact of environmental toxins on in vivo gametes (1:30); the effect of embryo vitrification on neonatal outcomes (15:40); impact of compressive force on gene expression in uterine fibroids (31:17); the role of automation in the IVF lab (42:25).

F&S Reviews: https://www.fertstertreviews.org/article/S2666-5719(25)00004-0/fulltext F&S Reports: https://www.fertstertreports.org/article/S2666-3341(25)00112-6/fulltext F&S Science: https://www.fertstertscience.org/article/S2666-335X(25)00048-5/fulltext Consider this: https://www.fertstert.org/news-do/potential-automated-ivf-lab

View the sister journals at:

• https://www.fertstertreviews.org
• https://www.fertstertreports.org
• https://www.fertstertscience.org

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:

08:57 Trends in Use of Preimplantation Genetic Testing for Aneuploidy Before Dobbs, After Dobbs Leak, and After Dobbs Final Ruling

20:12 The impact of PGT-A on time to live birth in IVF.

32:02 A Nationwide Analysis of the Trends in Permanent Contraception Utilization Before and After the Dobbs Ruling

37:28 Use of assisted reproductive technologies for male and female infertility and perinatal outcomes

50:50 Assisted hatching decreases pregnancy outcomes in vitrified donor oocytes

56:42 Use of medically assisted reproduction and the risk of multiple live birth across sexual orientation groups—results from a national longitudinal cohort

View the August 2025 issue, Vol 124: Issue 2 - https://www.fertstert.org/issue/S0015-0282(25)X0008-X

View Fertility and Sterility at https://www.fertstert.org/

In this month's Fertility & Sterility: Unplugged, we take a look at articles from F&S's sister journals!

Topics this month include: whether drug-free in vitro activation with immediate autotransplantation improved reproductive outcomes in patients with poor ovarian response and premature ovarian insufficiency (2:13); resident management of pregnancy of unknown location (16:42); integration of mental health treatment into the care of Mullerian agenesis (26:38), and a narrative review of blastocyst development as a surrogate for pregnancy outcomes (36:27).

F&S Science: https://www.fertstertscience.org/article/S2666-335X(25)00040-0/abstract Consider this: https://www.fertstert.org/news-do/beta-book-beta-overlooked-exploring-systems-pul-surveillance-residency F&S Reports: https://www.fertstertreports.org/article/S2666-3341(25)00057-1/fulltext F&S Reviews: https://www.fertstertreviews.org/article/S2666-5719(25)00008-8/fulltext

View the sister journals at:

• https://www.fertstertreviews.org
• https://www.fertstertreports.org
• https://www.fertstertscience.org

Take a sneak peak at this month's Fertility & Sterility! Articles discussed this month are:

03:32 How Many Infants Have Been Born With the Help of Assisted Reproductive Technology?

11:33 Adding Short-Duration Gonadotropin-Releasing Hormone Antagonist and Gonadotropin to Natural Cycle Frozen Embryo Transfer Allowed Scheduling of Transfer Day Without Compromising Live Birth

24:42 Sublingual Progesterone Lozenges Are a Viable Alternative to Intramuscular Porgesterone-in-Oil for Programmed Frozen Embryo Transfer Cycles

33:08 Perinatal Outcomes of Progesterone in Natural Frozen-Thawed Embryo Transfer Pregnancies: Insights From 2 Randomized Controlled Trials

42:38 Cost Effectiveness Analysis of Uterus Transplantation vs. Gestational Carrier for Treatment of Absolute Uterine Factor Infertility in the United States AND Comparing Gestational Carrier with Uterine Transplantion in Uterine-Factor Infertility: A Cost-Effectiveness Analysis

01:03:28 Extended Intrauterine Balloon Stent Use to Prevent Adhesion Reformation After Hysteroscopic Adhesiolysis, A Randomized Trial

View the July 2025 issue, Vol 124: 1-178 - https://www.fertstert.org/issue/S0015-0282(25)X0006-6

View Fertility and Sterility at https://www.fertstert.org/