Spring is a time when many of us think about fresh starts and better health, including the well-being of our pets. This week on Foodie Pharmacology, Dr. Cassandra Quave speaks with Angela Ardolino about natural approaches to supporting aging dogs. Angela, a formulator and educator specializing in cannabinoids, medicinal mushrooms, and adaptogens, explains how these compounds interact with the endocannabinoid system to regulate inflammation, neurological function, and overall balance. They discuss the differences between full-spectrum hemp extracts and isolated compounds, how cannabinoids may support joint pain, seizures, and cognitive decline, and the growing interest in functional mushrooms like lion’s mane, reishi, and cordyceps for brain health of our pets. The conversation also examines what cognitive decline looks like in aging pets, the role of inflammation and the gut-brain connection, and how diet and ultra-processed pet foods may contribute to disease. From reading supplement labels to understanding ingredient sourcing and quality, this episode offers a practical framework for pet owners interested in integrative approaches to animal health. Learn more about Angela’s work at https://angelaardolino.com/