A little more than 40 years ago, there was a live event that changed television forever. Muhammad Ali vs. Joe Frazier. A boxing match: "The Thrilla in Manilla."

But the men in the ring weren't the only ones with big career stakes on the line. A 30-year-old entrepreneur named Kay Koplovitz had waited about a decade for this moment. She was the driving force behind making the fight the first live satellite broadcast. It changed the cable industry forever, and laid the groundwork for her to become the first woman to head a television network – one she launched two years later – USA Network. 

Kay Koplovitz today is a venture capital investor, a board member, and an advocate for women in business. I got some time with her on a busy day at the Nasdaq Marketsite in Times Square to talk about her journey, and lessons for the rest of us who – maybe in our jobs, maybe with some new venture – are trying to do what's never been done. 

Sometimes Plan A doesn’t work out. You’ve got to be ready to improvise. 

That’s one of the themes in Bastian Lehman’s story. He had a different career path in mind, but ended up settling for entrepreneurship. So far it’s going pretty well. He’s the cofounder and CEO of Postmates, a delivery startup that’s part of this race to remake the way we shop. He's raised about a quarter billion dollars.  

Postmates was originally supposed to be doing furniture delivery. That didn’t work out for some interesting reasons. When I sat down with Bastian Lehmann at the New York Stock Exchange, I got a fresh appreciation for why the ability to make smart adjustments is often better than being able to divine the future. 

I’ve never had a repeat guest on Fortt Knox in the year and a half I’ve been doing this. That’s not because there’s a rule against it, I just never had a compelling reason to.  

That changes this week.  

A few days ago I flew out to Seattle and then went up to Microsoft’s headquarters in Redmond, and sat down with CEO Satya Nadella. Satya was my guest in October, when his book "Hit Refresh" came out. It was a big deal because Nadella has dramatically changed the perception and trajectory of one of the world's most iconic companies, and most people had no clue who he is. "Hit Refresh" was his big moment of public definition, both for his vision for Microsoft and for himself as a leader. 

Satya wasn't new to me, though. We first met about seven years ago, before he was CEO, on one of his trips to Silicon Valley. I was CNBC's tech correspondent, he was in charge of Microsoft's Server and Tools division, which at the time most people outside of the tech industry thought was a boring backwater. The bright spotlight was on phones, PCs, Xbox, even search. Little did the masses know that the future was in cloud, and Satya Nadella's division would keep Microsoft relevant. 

So – fast forward to today, May 2018. Microsoft has its Build developer conference in Seattle, and Satya took some time ahead of it to talk about his vision for the company's platforms; his chief rivals in the cloud, Amazon and Google; his views on data privacy after Facebook's Cambridge Analytica scandal; his view on U.S. trade tensions with China, and a lot more.  

A quick correction – when I'm ribbing him in the beginning about his book tour, I say he was in Better Homes and Gardens. It was actually Good Housekeeping. Go figure. 

Vlad Shmunis just wasn't an enthusiastic employee. Didn't like following directions. And he had ideas – lots of ideas. Eventually, something had to give. So the entrepreneurial engineer took a leap, even though family members said he was nuts. 

How'd that work out? Well today, Vlad Shmunis is the founder and CEO of RingCentral, a Silicon Valley company at the intersection of communication and cloud. The company went public just under five years ago. Today it's worth more than $5 billion. 

If you're a long-time Fortt Knox listener, you're going to sense a pattern. Vlad is the third CEO I've had on who grew up in the former Soviet Union and eventually found his way to the U.S. There was Citrix CEO Kirill Tatarinov, Coupa CEO Rob Bernshteyn, and now Vlad. Their stories are all pretty different in key details, but similar in some important core ways, when it comes to education, values and … please listen for this one … the family's approach to risk. 

If you or someone you know is thinking about taking a leap to start your own thing, but you're not quite sure, listen to Vlad's story.

Rafat Ali has done something remarkable in an era where it's really tough to make money telling people the truth. He built and sold PaidContent, a site that covered the digital media revolution with trenchant foresight. And now he's built Skift, an information company focused on the travel and dining industries. 

I sat down with Rafat Ali at the Nasdaq Marketsite in Times Square to get an insider's look at how you revolutionize a crumbling industry. Rafat's a guy whose career I've sort of passively followed as a journalist for a long time. When I was writing for a newspaper in Silicon Valley 18 years ago, I saw him toughing it out on the opposite coast. As he's jumped into entrepreneurial ventures, I leaped from newspapers, to magazines, to broadcast, while crafting my own digital projects. Like Fortt Knox. 

Anyway, part of the brilliance of Rafat Ali is his ability to draw lessons from one industry that are prophetic in another. So even if you're not into media or travel, there's something in here for you. 

GoFundMe is a generosity powerhouse – it's helped people raise a total of more than 5 billion dollars for all kinds of causes and pet projects. Rob Solomon is its CEO. Late last year, Solomon made a bold move – GoFundMe no longer takes an automatic cut of the money people raise. Now GoFundMe itself runs purely on donations. 

Solomon didn't think he wanted to be the CEO of GoFundMe when he first got the offer – he saw people using it to raise money for cat toys – but he soon changed his tune. I talked to him about the future of using tech to do good, the primacy of trust in today's landscape, and his advice for Facebook's Mark Zuckerberg, who's facing his own trust crisis. 

Tim Ryan grew up in a working-class family in Boston, where his early jobs included a paper route and a job at a grocery. He’s now the U.S. chairman of PriceWaterhouseCoopers, the global accounting firm known as one of the big 4 auditors. In 2016 it was ranked as the fifth largest private employer in America.  

Whether it’s the changing political landscape, the headaches companies face over protecting data, or getting the right envelopes at the Oscars, PwC handles issues large and small – and a lot of it crosses Ryan’s desk.  

I sat down with Tim Ryan at PwC’s office on Madison Avenue in Manhattan to talk about the challenges facing global business, and his own rise from blue-collar roots to the top level of a company that touches many of the world’s most powerful companies.

This week on the podcast? DoorDash cofounder and CEO Tony Xu. He just raised more than half a billion dollars to build out his business. 

There’s this idea out there that today’s consumers are lazy, and that’s why we're getting stuff delivered all the time. The thing is, I don’t know about you – but the reason why I’m ordering so much delivery is because I’m so busy.  

That’s where DoorDash comes in. The company was cooked up by four students at Stanford four and a half years ago. One of the four, Tony Xu, is the company's 33-year-old CEO. 

Xu was in New York recently after raising a monster round of funding – $535 million. I sat down with him at the Nasdaq MarketSite in Times Square to find out what he's really building, and why he thinks he can beat Grubhub, Amazon, Google, and a lot more rivals lining up to take him on. 

Everybody loves a David and Goliath story. The problem is, in business these days, the David is usually a family business, and the Goliath is some technology-juicing giant. Goliath is usually winning. 

So here's a story that returns to classic form: Danny Govberg is the CEO of Govberg Jewelers in Philadelphia – and he's also the CEO of Watchbox, an app and website that's shaking up the world of luxury watches. By Govberg's count, he's selling at a rate of $200 million worth of watches this year between the two businesses, much of it in brands like Rolex, Patek Phillipe and Omega – brands that run in the thousands and tens of thousands of dollars per watch. And he says he's growing more than 30% a year. 

All of this is happening while the popular narrative is stacked against him. Supposedly hardly anyone wears watches anymore, and for those that do, the Apple Watch and Samsung Watch are running roughshod over the market. Well? That's not the whole story. 

I met Danny Govberg at the Breitling Boutique on Madison Avenue in Manhattan – you'll hear the sounds of the store and some construction next door. We talked about how the business evolved from his immigrant grandfather's beginnings as a watchmaker, and why technology is growing his old family business while it's killing others.

Abe Ankumah had never touched a computer before he arrived at Caltech in 1997, but quickly became captivated and decided to major in computer science. Now he’s the cofounder and CEO of Nyansa, a Silicon Valley startup that monitors the health of wireless networks.

An immigrant from Ghana, raised by hopeful entrepreneurs, he has the kind of story that has fueled Silicon Valley for decades.

I met Abe at the Nasdaq MarketSite in Times Square and talked to him about his journey, and the experiences that paved the way for what he's working on now.